1992
DOI: 10.1097/00002341-199206000-00003
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Evaluation of a Collagen/Hydroxylapatite Implant for Orbital Reconstructive Surgery

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Cited by 17 publications
(8 citation statements)
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“…Biomimetically, one can achieve an oriented growth of CDHA crystals onto dissolved collagen fibrils in aqueous solutions via a selforganization mechanism [628]. A number of authors produced calcium orthophosphate/collagen biocomposites by mixing preformed ceramic particles with a collagen suspension [635][636][637]. However, in all blended composites, the crystallite sizes of calcium orthophosphates were not uniform and the crystals were often aggregated and randomly distributed within a fibrous matrix of collagen.…”
Section: Biocomposites With Collagenmentioning
confidence: 99%
“…Biomimetically, one can achieve an oriented growth of CDHA crystals onto dissolved collagen fibrils in aqueous solutions via a selforganization mechanism [628]. A number of authors produced calcium orthophosphate/collagen biocomposites by mixing preformed ceramic particles with a collagen suspension [635][636][637]. However, in all blended composites, the crystallite sizes of calcium orthophosphates were not uniform and the crystals were often aggregated and randomly distributed within a fibrous matrix of collagen.…”
Section: Biocomposites With Collagenmentioning
confidence: 99%
“…747 A number of authors produced calcium orthophosphate/collagen biocomposites by mixing preformed ceramic particles with a collagen suspension. [765][766][767] However, in all blended composites, the crystallite sizes of calcium orthophosphates were not uniform, and the crystals were often aggregated and randomly distributed within a fibrous matrix of collagen. Therefore, no structural similarity to natural bone was obtained, and only a compositional similarity to that of natural bone was achieved.…”
mentioning
confidence: 98%
“…Hydroxyapatite-collagen composites have been prepared by many workers in different forms [8,10,[13][14][15]. In our attempt hydroxyapatite particles were gradually added to deionized water and intensively mixed.…”
Section: Preparation Of Hydroxyapatite-collagen Compositesmentioning
confidence: 99%
“…One of the earliest attempts to develop collagen-calcium phosphate composite was made by Mittlmier and Nizzard [11] who mixed calcium phosphate granules with collagen web. Many other researchers attempted to produce these composites by mixing the preformed calcium phosphate granules in collagen suspension [10][11][12][13][14]. However, very few of these attempts considered the mechanical strength of the composites that suits their realistic uses.…”
Section: Introductionmentioning
confidence: 99%