| Newly born male Friesian calves (n=15) with average live body weight (LBW) of 35.07±0.63 kg after calving were divided into three groups (5 in each). Calves were fed colostrum from their dams for the first three days of age then whole milk meals were fed and the starter plus good quality berseem hay were given after the second week of age. In the first group, calves had no treatment and considered as control (G1), while those in G2 and G3 were received an oral dose of Thymus vulgaris extract (THY) at levels of 20 and 40 mg per kg BW, respectively. Treatment lasted from 3 up to 105 d of age. Results show that THY at 40 mg/kg LBW increased (P<0.05) serum immunoglobulins (IgG, IgM and IgA), hematological parameters, serum total lipids and cholesterol, improved liver and kidney functions and health status of the calves, while decreased diarrheal incidence. In conclusion, oral administration with thyme extract at a level of 40 mg/kg body weight to Frisian calves, during the suckling period had beneficial effects on their immunity and health status, consequently improving their growth rate and live body weight, which could help farmers to raise the suckling calves for breeding or milk and meat production to relieve milk and beef lack in Egypt.