Evaluation of 14- and 11-gauge directional, vacuum-assisted biopsy probes and 14-gauge biopsy guns in a breast parenchymal model.

Abstract

Statistically significant differences with various biopsy devices are seen in the breast tissue yield and in fragmentation.

Biopsy of breast microcalcifications using an 11-gauge directional vacuum-assisted device.

“…Mean specimen weights of 94 mg for the former versus less than 18 mg for the latter have been reported [7]. This increase in tis with published results [5,6].…”

Predictive factors for invasive cancer in surgical specimens following an initial diagnosis of ductal carcinoma in situ after stereotactic vacuum-assisted breast biopsy in microcalcification-only lesions

“…Sim et al (17) reported that the underestimation rate of DCIS (26%) was significantly higher when preoperative biopsies were performed using core biopsy needles, compared with the lower underestimation rate of DCIS (19.9%) in biopsies obtained using VAB devices. Although SVAB allows more accurate histopathologic results, underestimation still occurs (7,10,18). Some investigators have found rates of underestimation ranging from 5% to 29% for DCIS at SVAB (6,9,(11)(12)(13).…”

“…Large core SVAB allows larger samples to be obtained in a shorter period of time compared with samples obtained using automated core biopsy devices (7). Moreover, this technique has the advantage of a single insertion in the area of interest compared with automated core biopsy…”

Factors that impact the upgrading of atypical ductal hyperplasia

“…The rate of underestimation of ADH has been reported to range from 11% to 65% for 14-gauge automated biopsy (14)(15)(16)(17)(18)(19)(20). Technical advances in percutaneous core needle biopsy, such as increasing needle diameter from 14-gauge to 11-gauge and adding a vacuum device, have allowed larger samples of tissue to be obtained (5,6), substantially improving the accuracy of diagnosis. Despite these improvements, the rate of underestimation for ADH has been reported as 10% to 26% for 11-gauge vacuum-assisted biopsy (VAB) (2,14,(21)(22)(23)(24)(25)(26)(27)(28).…”