Evaluation in mice of cell-free produced CT584 as a Chlamydia vaccine antigen
Steven Hoang-Phou,
Sukumar Pal,
Anatoli Slepenkin
et al.
Abstract:Chlamydia trachomatisis the most prevalent bacterial sexually transmitted pathogen worldwide. Since chlamydial infection is largely asymptomatic with the potential for serious complications, a preventative vaccine is likely the most viable long-term answer to this public health threat. Cell-free protein synthesis (CFPS) utilizes the cellular protein manufacturing machinery decoupled from the requirement for maintaining cellular viability, offering the potential for flexible, rapid, and de-centralized productio… Show more
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