Evaluation for therapeutic measures to small gastric stromal tumor: A retrospective study of 90 cases

Zhao, Qun; Yong, Li; Yang, Peigang; Zang, Yanqiu; Fan, Li; Tan, Bibo; Tian, Yuan

doi:10.1016/j.currproblcancer.2018.01.012

Cited by 2 publications

(1 citation statement)

References 22 publications

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“…Previous studies have indicated that the stomach is the most frequent location for primary GISTs, followed by the small intestine, colon, rectum, and esophagus [ 2 , 7 , 8 ]. Moreover, gastric GISTs present with a smaller size and fewer symptoms compared with GISTs at other sites [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Efficacy and Safety of Endoscopic Resection for Small Gastric Gastrointestinal Stromal Tumors in Elderly Patients

Cai

Yang

Ren

et al. 2022

Gastroenterology Research and Practice

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Background. Gastrointestinal stromal tumors (GISTs) are prevalent in elderly patients. Endoscopic resection has become popular for treating small (≤5 cm) gastric GISTs. However, little is known about the outcomes of endoscopic resection in elderly patients. Aim. To assess the efficacy and safety of endoscopic resection for small (≤5 cm) gastric GISTs in elderly patients (≥65 years old). Methods. A total of 260 patients (265 lesions) with gastric GISTs treated via endoscopic resection from January 2011 to May 2020 were retrospectively analyzed. Among them, 65 patients were ≥65 years old (elderly group), and 195 patients were <65 years old (nonelderly group). Clinicopathological characteristics, postoperative complications, and tumor recurrence rates between the two age groups were compared. Results. A total of 260 patients with primary small (≤5 cm) gastric GISTs were treated with endoscopic resection. The median ages of the elderly and nonelderly groups were 68 (range 65-83) years and 55 (range 32-64) years, respectively. Elderly patients showed a higher incidence of comorbidities compared with nonelderly patients (61.5% versus 32.3%s, respectively; p < 0.001 ). All elderly patients and 99.0% of nonelderly patients underwent en bloc resection; only two nonelderly patients received piecemeal resection. No significant differences were found regarding postoperative complications or tumor recurrence rates between the two groups. Conclusions. Although elderly patients had more comorbidities than nonelderly patients, both groups had similar postoperative complications and recurrence rates. We suggest that endoscopic resection performed by experienced endoscopists is safe and effective for treating small (≤5 cm) gastric GISTs in elderly patients.

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Section: Introductionmentioning

confidence: 99%