Évaluation de l’effet antilithiasique, oxalo-calcique et phospho-ammoniaco-magnésien d’extrait aqueux d’ Erica multiflora L.

Sadki, Chrifa; Atmani, Fouad

doi:10.1016/j.purol.2017.09.011

Cited by 8 publications

(5 citation statements)

References 19 publications

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“…In contrast, rats treated with essential oils at 25 µl/kg and ethanolic extract at 200 mg/kg showed lower weight gain than the other groups, with respective percentages of 24 % ± 0.01 and 22 % ± 0.04. These results are not compatible with the work of ( Sadki and Atmani, 2017 ), whose study shows that the ethylene glycol-induced group gained more weight than the group treated with the aqueous extract of E. multiflora . Fig.…”

Section: Discussioncontrasting

confidence: 91%

The Anti-urolithiatic effect of the roots of Saussurea costus (falc) Lipsch agonist ethylene glycol and magnesium oxide induced urolithiasis in rats

Mammate,

El Oumari,

Imtara

et al. 2024

Saudi Pharmaceutical Journal

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Section: Discussioncontrasting

confidence: 91%

The Anti-urolithiatic effect of the roots of Saussurea costus (falc) Lipsch agonist ethylene glycol and magnesium oxide induced urolithiasis in rats

Mammate,

El Oumari,

Imtara

et al. 2024

Saudi Pharmaceutical Journal

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“…Microscopic crystallization of struvite, as shown in Table 1 and Figure 2 , Figure 3 and Figure 4 , indicated that the number of crystals were decreased upon increasing the concentration of the studied extracts. Our data also revealed that the S. costus ethanolic extract was effective against struvite and can also suppressed the ammonium–magnesium phosphate crystals formation, since the number of crystals remaining at a concentration of 1 mg mL −1 is 100/mm 3 ; thus, these results are similar to those of Sadki et al [ 21 ]. Their research revealed that the studied plant is effective, with the number of crystals reaching 100/mm 3 at a concentration of 1 mg mL −1 .…”

Section: Discussionsupporting

confidence: 91%

“…The purpose of this experiment was to see how extracts of the plant S. costus affected struvite crystals in the presence and absence of extracts. This experiment was performed using an in vitro struvite crystallization protocol described by C. Sadki et al [ 21 , 31 ] with some modifications. This protocol involves the preparation of two solutions: solution A, which consists of 0.1 M potassium dihydrogen phosphate (KH 2 PO 4 ), and solution Bm which consists of magnesium chloride (41 g), ammonium chloride (50 g) and 20 mL ammonium hydroxide diluted 10 fold in 50 mL of bi-distilled water.…”

Section: Methodsmentioning

confidence: 99%

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Anti-Struvite, Antimicrobial, and Anti-Inflammatory Activities of Aqueous and Ethanolic Extracts of Saussurea costus (Falc) Lipsch Asteraceae

et al. 2023

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Saussurea costus (Falc) Lipsch is a traditional herb used to treat kidney stone problems because it contains several molecules used to treat this health problem, such as quercitrin. Infectious stones are the most painful of all urinary tract disorders, with ammonium phosphate (struvite) and carbapatite stones being the most common, caused by a bacterial infection with urease activity. These stones are treated with antibiotics, but antibiotic resistance is on the rise. The current study investigated the anti-urolithic activities of S. costus aqueous and ethanolic extracts of against struvite crystals synthesized using microscopic crystallization and turbidimetric methods, respectively. The utilized methods indicated that the ethanolic extract of this plant has a significant inhibitory effect on struvite crystallization, with a percentage inhibition of (87.45 ± 1.107) (p < 0.001) for a concentration of 1 mg mL−1 and a decrease in the number of struvite crystals, reaching values less than 100/mm3. For the number of struvite crystals inhibited by cystone, we found a value of 400/mm3 and with the aqueous extract we found 700/mm3. The antibacterial activity of the plant extracts studied was examined against several urease-producing bacteria, and this activity was evaluated by qualitative and quantitative evaluation methods; the highest minimum inhibitory concentration was seen in the ethanolic extract, with an MIC of 50 mg mL−1 for Staphylococcus aureus followed by an MIC of 200 mg mL−1 for Klebsiella pneumoniae. It showed a minimal bactericidal concentration (MBC) against S. aureus and K. pneumoniae (>50 mg mL−1 and >200 mg mL−1, respectively). Furthermore, to determine the extract’s anti-inflammatory activity, in vivo anti-inflammatory activity was investigated in rats. The results show that at a dose of 400 mg kg−1, the ethanolic extract has a maximum edema inhibition of 66%.

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“…Moreover, E. multiflora has shown antihyperlipidemic and liver function repair effects [8,9], and effective antilithiatic activity [10].…”

Section: Introductionmentioning

confidence: 99%

Determination of the Phenolic Profile by Liquid Chromatography, Evaluation of Antioxidant Activity and Toxicity of Moroccan Erica multiflora, Erica scoparia, and Calluna vulgaris (Ericaceae)

et al. 2022

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This study aimed to investigate the phenolic profile and selected biological activities of the leaf and aerial extracts of three Ericaceae species, namely Erica multiflora, Erica scoparia, and Calluna vulgaris, collected from three different places in the north of Morocco. The phenolic composition of all extracts was determined by LC coupled with photodiode array and mass spectrometry detection. Among the investigated extracts, that of E. scoparia aerial parts was the richest one, with a total amount of polyphenols of 9528.93 mg/kg. Up to 59 phenolic compounds were detected: 52 were positively identified and 49 quantified—11 in C. vulgaris, 14 in E. multiflora, and 24 in E. scoparia. In terms of chemical classes, nine were phenolic acids and 43 were flavonoids, and among them, the majority belonged to the class of flavonols. The antioxidant activity of all extracts was investigated by three different in vitro methods, namely DPPH, reducing power, and Fe2+ chelating assays; E. scoparia aerial part extract was the most active, with an IC50 of 0.142 ± 0.014 mg/mL (DPPH test) and 1.898 ± 0.056 ASE/mL (reducing power assay). Further, all extracts were non-toxic against Artemia salina, thus indicating their potential safety. The findings attained in this work for such Moroccan Ericaceae species, never investigated so far, bring novelty to the field and show them to be valuable sources of phenolic compounds with interesting primary antioxidant properties.

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Évaluation de l’effet antilithiasique, oxalo-calcique et phospho-ammoniaco-magnésien d’extrait aqueux d’ Erica multiflora L.

Cited by 8 publications

References 19 publications

The Anti-urolithiatic effect of the roots of Saussurea costus (falc) Lipsch agonist ethylene glycol and magnesium oxide induced urolithiasis in rats

The Anti-urolithiatic effect of the roots of Saussurea costus (falc) Lipsch agonist ethylene glycol and magnesium oxide induced urolithiasis in rats

Anti-Struvite, Antimicrobial, and Anti-Inflammatory Activities of Aqueous and Ethanolic Extracts of Saussurea costus (Falc) Lipsch Asteraceae

Determination of the Phenolic Profile by Liquid Chromatography, Evaluation of Antioxidant Activity and Toxicity of Moroccan Erica multiflora, Erica scoparia, and Calluna vulgaris (Ericaceae)

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