Évaluation de l’apport de l’immunohistochimie dans le diagnostic des angiosarcomes

Darré, Tchin; Amégbor, Koffi; Omorou, M.; Bissa, Haréfétéguéna; Pegbessou, Essobozou; Amana, B; Agoda, P; Boko, E; Napo‐Koura, Gado

doi:10.1007/s12558-013-0247-z

Cited by 4 publications

(3 citation statements)

References 9 publications

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“…Angiosarcoma may be confused with vascular tumors of intermediate malignancy (e.g., epithelioid and spindle cell hemangioendotheliomas, histioid hemangioma, and malignant endovascular papillary angioendothelioma) [1, 3, 4]. Hemangioperycitoma is a designation for vascular tumors that are a histological intermediate in appearance between a hemangioma and a conventional angiosarcoma.…”

Section: Discussionmentioning

confidence: 99%

“…CD34 may be only focally positive, or in some cases negative. CD31 is more sensitive than CD34, although its sensitivity decreases with more solid and undifferentiated angiosarcoma [4, 13]. The same occurs with Factor 8 because it is a marker of differentiated endothelial cells.…”

Section: Discussionmentioning

confidence: 99%

“…AS are prevalent in the adult subjects and ovarian localization is rarely described in the literature. Like most malignant tumors, the diagnosis of certainty is done by the conventional histology technique and the immunohistochemical testing with the positivity of specific markers of the vascular endothelium [4]. We report a case of primary angiosarcoma of the ovary in a 12-year-old girl in a resource-constrained context.…”

Section: Introductionmentioning

confidence: 99%

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Primary ovarian angiosarcoma in a 12- year -old girl: a case report of an exceptional localization in a context of limited resources country

et al. 2017

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BackgroundOvarian sarcomas represent less than 1% of all ovary cancers and usually are frequent in adults. Primary angiosarcomas are exceptional in the ovaries within children.Case presentationWe reported a case of primary ovarian angiosarcoma in a 12-year-old girl in a resource-constrained context. Immunohistochemistry study showed the positivity of CD34, CD31, factor VIII, while S100 was negative. The diagnosis of primary non-metastatic angiosarcoma was retained. She was unable to undergo the CWS-2002P chemotherapy since her parents could not afford it.ConclusionThis case report described a rare type of a primary ovarian angiosarcoma within a child, diagnosed in a low-income country in a laboratory with limited resources.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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