Evaluation clinical, electrocardiographic and laboratory response of reperfusion therapy in patients with first acute myocardial infarction

Abstract

Introduction: Myocardial infarction (MI) therapy is one of the most common causes of death and health issue in the world, especially in developed countries. Thrombolytic administration is a preferred life saver method of acute MI if primary angioplasty is not possible. Given that the incidence of MI in patients with metabolic syndrome, so evaluation of therapeutic response to streptokinase in this regard is very important. Methods: In this descriptive analytical study, 340 acute coronary syndrome patients which have study inclusion criteria divided randomly in two groups (with and without metabolic syndrome each with 170 patients) and collected data analyzed by statistical methods using SPSS 20. Results: Pain improvement after treatment in the group without metabolic syndrome was significantly higher than another group (58.2% vs. 23.4%) (P = 0.001). ST-segment resolution at 90 min after treatment in the group without metabolic syndrome significantly higher than another group (P = 0.002). Conclusion: Results showed that using of angioplasty is recommended as the preferred method instead of thrombolytic treatment in patients with metabolic syndrome suffering from MI.