Evaluation and treatment of metabolic syndrome and cardiovascular disease in adult patients with psoriasis

Abstract

Psoriasis is strongly associated with cardiovascular disease (CVD) and metabolic syndrome, with patients having an approximately twofold increased risk of each compared to the general population. This increased risk is based on shared underlying genetic and cytokine profiles, as well as similar environmental risks. Many screening guidelines do not address the development of CVD and metabolic syndrome in these predisposed patients. These deficits are evidenced by the exclusion of psoriasis as a risk factor in validated 10‐year CVD risk calculators for adult patients with chronic inflammatory diseases, as well as insufficient screening guidelines for insulin resistance in patients with psoriasis. This manuscript aims to discuss and propose allopathic and lifestyle recommendations for the screening and management of the aforementioned comorbidities in adult patients with psoriasis.

Efficacy of probiotic supplementation in the treatment of psoriasis—A systematic review and meta‐analysis

“…Meanwhile, more and more researches showed that psoriasis is always associated with metabolic syndrome. Psoriasis also is considered as an independent risk factor for cardiovascular disease 31 . Some researches found probiotic supplements, such as inulin and fructooligosaccharides could decrease cholesterol and triglyceride levels in both in vivo and in vitro studies 32 .…”

“…Psoriasis also is considered as an independent risk factor for cardiovascular disease. 31 Some researches found probiotic supplements, such as inulin and fructooligosaccharides could decrease cholesterol and triglyceride levels in both in vivo and in vitro studies. 32 A study also reported probiotic supplements decreased uric acid.…”