Evaluation and Treatment of Community-Acquired Staphylococcus aureus Infections in Term and Late-Preterm Previously Healthy Neonates

Abstract

Evaluation and treatment strategies for neonatal community-acquired S. aureus disease are varied at our hospital. Prospective studies are needed to determine optimal management strategies.

Outcomes After Skin and Soft Tissue Infection in Infants 90 Days Old or Younger

“…8,10,11 One study of 104 afebrile infants #28 days who presented to the ED for SSTI found that none had IBI. 10 Another study of infants #30 days identified as having superficial or invasive S aureus infection found that of the 68 patients (total study cohort 126 patients) with cellulitis/abscess, 2 (3%) had bacteremia and none had concomitant UTI or meningitis.…”

“…10 Another study of infants #30 days identified as having superficial or invasive S aureus infection found that of the 68 patients (total study cohort 126 patients) with cellulitis/abscess, 2 (3%) had bacteremia and none had concomitant UTI or meningitis. 11 A third study assessed the rate of UTI/IBI in well-appearing infants (aged ,60 days) presenting to the ED and diagnosed with focal bacterial infectionsincluding otitis media, lymphadenitis, and a variety of SSTIs (cellulitis, abscess, impetigo, paronychia). Although the study included a total of 197 patients, in the subset of patients with SSTIs (n 5 136), 3 patients (2.2%, all of whom were febrile) had UTI or IBI (1 with Streptococcus pneumoniae bacteremia and 2 with Escherichia coli UTI).…”

“…Data from the 2010 US census showed that Utah had an estimated total population of 2.76 million people (vs Houston, Texas, with 2.1 million people where a single-center study with similar patient numbers discussed earlier was located). 11,19 Furthermore, the demographic of Utah (79.7% white, non-Hispanic/Latino vs 62.6% in general United States 19 ) and MRSA rates may differ from other geographic regions. Geographic variation in the incidence of MRSA infections have also been well described, [20][21][22] unlike other geographic areas, Utah did not experience a large increase in community-associated MRSA during the study period.…”

“…[8][9][10] Previous single-center studies in tertiary children' s hospitals in urban settings have explored risks of UTI or IBI in infants with SSTI or Staphylococcus aureus infections; however, revisits for treatment failures or missed UTI/IBI outcomes may not have been captured because of the study setting. 8,10,11 Our study, using a multicentered approach over a range of hospital types including rural and urban settings in a network well suited to capture missed concomitant infections or treatment failures, could help to guide optimal clinical management including indication for workup of concomitant infections and follow-up planning. Therefore, our objective was to describe clinical outcomes for infants presenting to the hospital for concern of SSTI (with and without fever) including rates of UTI, IBI, and hospital revisit for treatment failure or missed concomitant bacterial infection as well as factors associated with treatment failure.…”

Neonatal Mastitis After Breast Massage: A Case Report

“…Yenidoğan dönemindeki geçici meme büyümesi cinsiyet farkı göstermez ve genelde doğumdan birkaç gün sonra başlar, en fazla 4.-6. ayda kendiliğinden kaybolur. Eritem ve sıcaklık artışı gözlenmez (1,2) . Ülkemizde genellikle aile büyükleri tarafından bu durum bir hastalıkmış gibi algılanmakta ve meme üzerine para koyma, meme dokusunu sıkma veya masaj uygulama gibi yöntemlerle sorun çözülmeye çalışılmaktadır.…”