Evaluation and Treatment of Acute Trauma Pain in Older Adults

Merrick, Minnie; Grange, Robert; Rudd, Sarah; Shipway, David

doi:10.1007/s40266-023-01052-2

Cited by 3 publications

(1 citation statement)

References 78 publications

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“…Intravenous (IV) analgesia is often delivered in the primary post-operative episode, as oral administration is less practicable ( 3 ). In moderately severe to severe post-operative acute pain, guidelines advocate the use of potent opioids like morphine, fentanyl, oxycodone, or hydromorphone within the aspect of a multimodal analgesic strategy ( 4 ).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Effectiveness and Safety of Oxycodone Hydrochloride and Fentanyl for Post-operative Pain Following Total Hip Arthroplasty: A Randomized Triple-Blind Trial

Kohaf,

Harby,

Abd-Ellatief

et al. 2024

Anesth Pain Med

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Background: Total hip replacement (THR) is frequently associated with intense post-surgical pain. Effective pain management is of crucial importance to improving patient's condition and increasing his/her satisfaction in the post-operative time. Objectives: This study aimed to compare the analgesic effect and safety of oxycodone and fentanyl after THR. Methods: Seventy-two cases scheduled for elective THR were included in this randomized, triple-blind trial. The patients were equally randomized into 2 groups: fentanyl group (50 ug of fentanyl) and oxycodone group (oxycodone 4 mg). Drugs were received 20 min prior to the end of the operation. Results: Post-operative visual analog scale (VAS) measurements at rest and movement at the post-anesthesia care unit (PACU) and in the ward, 2 h, 4 h, and 8 h post-operatively exhibited a significantly reduced value in the oxycodone group compared to the fentanyl group (P-value < 0.05). Time to first rescue for analgesia was delayed significantly in the oxycodone compared to the fentanyl group (P-value < 0.001). Fentanyl consumption (ug) in the 1st post-operative 12 h, 24 h, and 48 h decreased significantly in the oxycodone group compared to the fentanyl group (P-value < 0.001). Post-operative nausea, vomiting, headache, and pruritus were matched between the 2 groups (P > 0.05). Conclusions: A bolus dose of 4 mg of oxycodone provided superior analgesic efficacy than 50 ug fentanyl as evidenced by significantly lower pain score, delayed onset to first request for analgesia, and the smaller amount of fentanyl consumption at 12, 24, and 48 h post-total hip arthroplasty compared to fentanyl. The incidence of adverse events was comparable between the 2 groups.

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Section: Introductionmentioning

confidence: 99%

Comparison of Effectiveness and Safety of Oxycodone Hydrochloride and Fentanyl for Post-operative Pain Following Total Hip Arthroplasty: A Randomized Triple-Blind Trial

Kohaf,

Harby,

Abd-Ellatief

et al. 2024

Anesth Pain Med

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Care of Geriatric Trauma Patients

Magidson,

Derry-Ehrler

2024

Curr Geri Rep

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A holistic approach to acute pain in trauma: From assessment to intervention

Shetti

2024

IJN

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Effective management of acute pain in trauma situations demands a comprehensive and holistic approach that encompasses various aspects ranging from initial assessment to intervention strategies. Meticulous assessment of pain severity, characteristics, and underlying etiology is essential for tailoring individualized treatment plans. This involves utilizing validated pain assessment tools, considering patient-reported pain scales, and integrating clinical judgment to accurately gauge pain intensity and quality.Subsequently, intervention strategies must be multifaceted, integrating pharmacological and non-pharmacological modalities to address pain effectively while minimizing adverse effects and promoting patient safety. Pharmacological interventions may include analgesics such as opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and adjuvant medications, administered judiciously based on pain severity and patient factors. Meanwhile, non-pharmacological approaches encompass techniques like regional anaesthesia, physical therapy, cognitive-behavioural therapy, and integrative therapies to augment pain relief and enhance overall well-being.

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Evaluation and Treatment of Acute Trauma Pain in Older Adults

Cited by 3 publications

References 78 publications

Comparison of Effectiveness and Safety of Oxycodone Hydrochloride and Fentanyl for Post-operative Pain Following Total Hip Arthroplasty: A Randomized Triple-Blind Trial

Comparison of Effectiveness and Safety of Oxycodone Hydrochloride and Fentanyl for Post-operative Pain Following Total Hip Arthroplasty: A Randomized Triple-Blind Trial

Care of Geriatric Trauma Patients

A holistic approach to acute pain in trauma: From assessment to intervention

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