2010
DOI: 10.1177/0897190010388150
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Evaluation and Management of Shock States

Abstract: Shock states have multiple etiologies, but all result in hypoperfusion to vital organs, which can lead to organ failure and death if not quickly and appropriately managed. Pharmacists should be familiar with cardiogenic, distributive, and hypovolemic shock and should be involved in providing safe and effective medical therapies. An accurate diagnosis is necessary to initiate appropriate lifesaving interventions and target therapeutic goals specific to the type of shock. Clinical signs and symptoms, as well as … Show more

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Cited by 30 publications
(8 citation statements)
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“…Vital organ hypoperfusion leads to shock, which, if not rapidly managed, is directly related to mortality. 11 Clinical signs, symptoms, and hemodynamic data of shock help to initially assess, monitor, and provide adequate resuscitation for the patient. Physical examination findings of shock and tissue hypoperfusion, vital signs, tissue perfusion measurement, biochemical markers of metabolism, CVP measurement, and ultrasound parameters help to assess volume status.…”
Section: Discussionmentioning
confidence: 99%
“…Vital organ hypoperfusion leads to shock, which, if not rapidly managed, is directly related to mortality. 11 Clinical signs, symptoms, and hemodynamic data of shock help to initially assess, monitor, and provide adequate resuscitation for the patient. Physical examination findings of shock and tissue hypoperfusion, vital signs, tissue perfusion measurement, biochemical markers of metabolism, CVP measurement, and ultrasound parameters help to assess volume status.…”
Section: Discussionmentioning
confidence: 99%
“…2 Inotropes should always be started when patient is well volume resuscitated. 9 It is important to identify and appropriately start inotropes to decease morbidity in resource limited setup like ours.…”
Section: Resultsmentioning
confidence: 94%
“…In fact, norepinephrine has increasingly proven to be of benefit in the management of hypovolemic and cardiogenic shock by either venous α or β 2 -adrenergic stimulation[ 18 19 20 ] and decreases myocardial oxygen consumption in situations of tachycardia and tachyarrhythmias. [ 21 22 ] It is also recommended as the first choice of vasopressors in European guidelines for the management of hemorrhagic and cardiogenic shock. [ 11 12 ] However, these guidelines have not been widely accepted to the same degree as those for septic shock.…”
Section: Discussionmentioning
confidence: 99%