Evaluation and management of shock in patients with COVID-19

Fox, Steven; Vashisht, Rishik; Siuba, Matthew; Dugar, Siddharth

doi:10.3949/ccjm.87a.ccc052

Cited by 14 publications

(21 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Furthermore, systemic hypoperfusion and capillary leakage and shock were reported to be present in COVID-19 patients. 35 At any rate, in our critically ill COVID-19 patients, hypoperfusion caused by circulatory impairment seemed not to play a role as systemic hypoperfusion markers did not indicate such a state, but local hypoperfusion and tissue hypoxia might still be an issue.…”

Section: Discussionmentioning

confidence: 63%

“…Therefore, it is not clear whether the differences found were due to the higher age or to the disease itself. Also, the healthy population could not be matched for other variables such as comorbidities and therefore (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22) 14 (10)(11)(12)(13)(14)(15)(16)(17) 31 (25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35) -17 (-20 to -14) <0.01 0/0 A20 (mm) 17 (12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24) 15 (12)(13)(14)(15)(16)(17)(18) 33 (27)…”

Section: Limitationsmentioning

confidence: 99%

See 1 more Smart Citation

Impaired fibrinolysis in critically ill COVID-19 patients

Bachler

Bosch

Stürzel

et al. 2021

British Journal of Anaesthesia

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 63%

Section: Limitationsmentioning

confidence: 99%

Impaired fibrinolysis in critically ill COVID-19 patients

Bachler

Bosch

Stürzel

et al. 2021

British Journal of Anaesthesia

View full text Add to dashboard Cite

“…Inotropic agents are frequently used in patients with concerns about severely reduced cardiac output, indicating a poor prognosis 30 . Indeed, patients requiring inotropic therapy had a lower one-month survival rate in this study.…”

Section: Discussionmentioning

confidence: 99%

Survival patterns of COVID-19 pneumonia patients with false-negative PCR results transferred to the intensive care unit from the emergency department

Kodik

2021

Preprint

View full text Add to dashboard Cite

ObjectiveThis study aimed to analyze factors associated with patient mortality in COVID-19 patients hospitalized in the intensive care unit (ICU) and provide data to help prioritize the most critical patients.DesignRetrospective cohort studySetting and participantsData for 289 patients were analyzed by the XXX hospital’s IT department.MethodsA clinical retrospective cohort study was conducted in a tertiary hospital. Patients (n=289) with negative reverse transcription-polymerase chain reaction (RT-PCR) and positive chest computed tomography (CT) scan indicating COVID-19 were included in the research. Demographics, clinical characteristics, treatment modalities, and length of hospital stay were analyzed in relation to 30-day survival outcomes.ResultsThe mean age of the patients was 69.04±15.10 years (range 19-100), and 41.2% (n=119) were female. The mortality rate was 48.1% (n=139). There were statistically significant differences in laboratory findings, such as hemoglobin (p=0.021), lymphocyte counts (p=0.046), d-dimer (p=0.009), and lactate (<0.001) regarding one-month survival. Additionally, those hospitalized for more than 5 days had higher one-month survival rates (hazard ratio (HR)= 0.003, CI= 10.264-155.972). Moreover, intubated patients had a higher mortality risk during this period (HR=4.15, CI=1.53-11.20).Conclusions and implicationsThe first five days of patients hospitalized in intensive care units due to COVID-19 pneumonia are critical. Besides, the need for intubation was another factor independently affecting survival. Clinicians should be alerted about the significance of these factors.

show abstract

“…Hydroxychloroquine with or without azithromycin can disrupt the electrical activity of the heart [17]. Multiple organ dysfunction syndromes (MODS) and shock are associated with severe COVID-19 infection and can eventually lead to death [18].…”

Section: Cardiovascular Complicationsmentioning

confidence: 99%

Complications of Covid-19: A Systematic Review and Meta-Analysis

Alonge

Ademusire

Epum

et al. 2021

Journal of Microbiology and Infectious Diseases

View full text Add to dashboard Cite

Objectives: COVID-19, primarily a respiratory disease, can have complications that affect all organ systems of the body. There is a paucity of systematic reviews on all the complications. In this systematic review and meta-analysis, we set out to summarize the complications of COVID-19 in all body systems and their prevalence.Methods: PubMed and Google Scholar were searched for eligible articles using predefined criteria. Database searching and extraction were performed by independent reviewers. Results:We identified 74 case reports/series and 15 observational studies. In both the case reports/series and observational studies, pulmonary complications were the most commonly reported, particularly pneumonia, followed by neurological complications in case reports/case series and hematological complications in observational studies. Atrial arrhythmias (1.7%) and acute myopericarditis (1.7%), liver injury (3.3%), acute kidney injury (8.8%), deep venous thrombosis (2.2%), ischemic stroke (12.2%), herpes zoster (1.1%), and diabetic ketoacidosis (1.1%) were the most reported cardiovascular, gastrointestinal, renal, hematological, neurological, dermatological, and endocrine complications respectively in case reports/series. However, acute myocarditis (100%), hypoproteinemia (15.9-28.8%), transient acute renal failure (49.9-90.1%), acute coagulopathy (16.5-28.4%), and ischemic stroke (1.3-3.9%) had the highest pooled prevalence for cardiovascular, gastrointestinal, renal, hematological, and neurological complications respectively in observational studies. Conclusion:The complications of COVID-19 are multi-systemic with pulmonary complications being the most commonly reported. Notwithstanding, healthcare professionals should be aware that COVID-19 is a differential diagnosis for even the rare but equally debilitating complications and should screen patients who develop these complications to rule out COVID-19 during the pandemic and beyond.

show abstract

Evaluation and management of shock in patients with COVID-19

Cited by 14 publications

References 47 publications

Impaired fibrinolysis in critically ill COVID-19 patients

Impaired fibrinolysis in critically ill COVID-19 patients

Survival patterns of COVID-19 pneumonia patients with false-negative PCR results transferred to the intensive care unit from the emergency department

Complications of Covid-19: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About