Evaluation and Comparison of Total Antioxidant Capacity of Saliva Between Patients with Recurrent Aphthous Stomatitis and Healthy Subjects

Rezaei, Fatemeh; Soltani, Taher

doi:10.2174/1874210601812010303

Cited by 11 publications

(7 citation statements)

References 35 publications

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“…On the other hand, the effects of oxidative stress in the oral cavity have proven to contribute to chronic inflammatory periodontal diseases, RAS, oral lichen planus, etc. [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women

Zovari

Parsian

Bijani

et al. 2020

International Journal of Dentistry

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Objective. In menopause, reduction of estrogen hormone affects oxidative stress process in serum. Oxidative stress in saliva plays a significant role in the pathogenesis of oral diseases. The aim of this study was to investigate the total antioxidant capacity and lipid peroxidation in the serum and saliva of premenopausal and postmenopausal women. Methods. In this case control study, 50 postmenopausal women (case group) and 48 premenopausal women (control group) were selected. The unstimulated whole saliva and serum of the postmenopausal and premenopausal women were collected. The total antioxidant capacity (TAC) of the saliva and serum was measured by ferric reducing antioxidant power (FRAP). Also, malondialdehyde (MDA) was measured by thiobarbituric acid reactive substance (TBARS) method for serum and saliva. Then, the obtained data were analyzed by SPSS 17, whereby Mann–Whitney test and Spearman’s correlation test were used. P < 0.05 was considered statistically significant. Results. The postmenopausal group had significantly lower mean serum TAC and higher mean serum MDA than the control group ( P < 0 < 001 and P < 0.01 , respectively). The mean salivary TAC and MDA, however, did not differ significantly between the case and control group ( P = 0.64 and P = 0.08 , respectively). Conclusion. In postmenopausal women, with elevation of serum MDA and reduction of serum TAC, the extent of serum oxidative stress grows, but MDA and TAC levels of saliva do not change.

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“…On the other hand, the effects of oxidative stress in the oral cavity have proven to contribute to chronic inflammatory periodontal diseases, RAS, oral lichen planus, etc. [31][32][33].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women

Zovari

Parsian

Bijani

et al. 2020

International Journal of Dentistry

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“…The oxidant-antioxidant status changes in the saliva depend on many factors, making the interpretation of occurred changes difficult (REZAEI & SOULTANI [13]).…”

Section: Discussionmentioning

confidence: 99%

“…1. like a defense mechanism against the tissue inflammation changes (a compensatory response against oxidative stress caused by periodontal disease) 2. having oral pain change the diet with taking more liquid food and juices that are generally rich in nutrients, vitamins and antioxidant compounds, thereby improving antioxidants status of whole body and saliva (REZAEI & SOULTANI [13]). Some studies have demonstrated the effect of nutrition on antioxidant levels of saliva to support this possibility (green tea intake increase the TAC of whole saliva in adults with significant periodontal problems (BAKHTIARI & al.…”

Section: Discussionmentioning

confidence: 99%

Studies regarding salivary total antioxidant activity in different types of orthodontic treatement

RĀDUCANU¹,

Mihai²,

CARAIANE³

et al. 2019

Rom Biotechnol Lett.

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The defensive mechanism of the human body includes a wide range of antioxidants (non-enzymatic and enzymatic) that can eliminate reactive oxygen species and prevent their harmful consequences on the host. Total antioxidant capacity (TAC) is a biomarker used to measure the antioxidant potential of body fluids and it may be the most relevant parameter for assessing the defense capabilities. Because of the cumulative effect of antioxidants, it is better to measure the combined activity of all the antioxidants (total antioxidant capacity) instead of measuring the activity of each agent separated. The aim of this study is to investigate the effect of different orthodontic appliances (fixed and removable-aligners) on salivary total antioxidant capacity and if is a correlation between TAC and oral injuries made by them. Three groups of subjects have been tested: one group of ten patients with metallic fixed appliances, one group of ten patients with aligners, and a control group consisting in ten subjects. 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was used for TAC assessment and salivary samples were obtained from all individuals before treatment, at two weeks from the beginning, at one and two month of treatment. Also, it was quantified the presence of the injuries in the mucosa (clinical parameter). The result shows that different types of orthodontic appliances increase differently the TAC and seems to be influenced by the injuries. KeywordsTotal antioxidant capacity (TAC), DPPH method, orthodontic aligners, fixed appliances.To cite this article: MĀDĀLINA RA, SEBASTIAN M, AURELIANA C, VICTORIA B.Studies regarding salivary total antioxidant activity in different types of orthodontic treatement.

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“…It is reported that the imbalance between oxidation and antioxidation is one of the causes of tissue damage in patients with RAU [6] . Malondialdehyde (MDA), one of the stable end products of lipid peroxidation, represents the aggravation of lipid peroxidation.…”

Section: Recurrent Aphthous Ulcer and Oxidative Stressmentioning

confidence: 99%

Relationship between Oxidative Stress and Several Common Oral Mucosal Diseases: A Review

2023

IJFM

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Free radicals include reactive oxygen species and reactive nitrogen, which are vital substances in the biological process of the body, which have a positive effect on the human body at normal concentrations. When the content of free radicals is too high, the body will activate the antioxidant system to defend against this damage in order to protect itself. The disorder of the balance between pro-oxidative and antioxidant reactions will lead to oxidative stress: excessive production of free radicals, and the body's antioxidant system cannot effectively resist this invasion, free radicals destroy the molecular tissues that make up DNA, proteins and lipids, followed by irreversible damage. Many studies at home and abroad have shown that patients with some oral mucosal diseases (recurrent aphthous ulcer, oral lichen planus, oral leukoplakia, oral submucosal fibrosis, burning mouth syndrome) often observe oxidative stress in oral tissue or saliva and blood, and explore many potential biomarkers. Through the study of the relationship between oxidative stress and oral mucosal diseases, it will be of guiding significance for the etiological exploration and treatment of oral mucosal diseases. This article reviews the latest research progress on the relationship between oxidative stress and several common oral mucosal diseases in recent years.

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Evaluation and Comparison of Total Antioxidant Capacity of Saliva Between Patients with Recurrent Aphthous Stomatitis and Healthy Subjects

Cited by 11 publications

References 35 publications

Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women

Evaluation of Salivary and Serum Total Antioxidant Capacity and Lipid Peroxidation in Postmenopausal Women

Studies regarding salivary total antioxidant activity in different types of orthodontic treatement

Relationship between Oxidative Stress and Several Common Oral Mucosal Diseases: A Review

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