Evaluation and Comparison of Anti Cholesterol And Antioxidant Potential of Allium Sativum, Zingiber Officinale, Allium Parvum and it’s Polyherbal Formulation

Abstract

Cholesterol is an essential sterol found in our body.However, with high cholesterol levels, fatty deposits can develop in the blood vessels and cause heart disorders. Hypercholesterolemia along with Non elimination of free radicals and its accumulation in the body, on the other hand causes serious disorders such as atherosclerosis, cancer, inflammatory joint disease, asthma, diabetes etc. Including some of the naturally available anti cholesterol and antioxidant agents would prevent such disorders in the long run, and this study aims in throwing limelight on three such natural ingredientsginger, garlic and small onions. The aim of this study is to evaluate and compare the anticholesterol and antioxidant potential of Allium sativum, Zingiber officinale, Allium parvum and it's polyherbal formulation. Pure extracts of ginger, garlic and small onions were prepared followed by its antioxidant potential analysis using DPPH Free radical scavenging activity, Nitric oxide radical scavenging activity and In vitro anti cholesterol activity. The results thus obtained were statistically compared with each other and also with the combination of the three extracts. Statistical analysis shows that the allium sativum (garlic) has the individual anti cholesterol and antioxidant activity a little more when compared to the other two, while Zingiber officinale (ginger) shows more antioxidant activity when compared to the other two extracts. Allium parvum (Small onion), has almost equal anti cholesterol and antioxidant activity. The combination of the extracts in the ratio 1:2:1 (garlic:ginger:small onion) shows almost equal anti cholesterol and antioxidant potential when compared to the standard. The above results show that including ginger, garlic and small onion extracts in regular diets can boost health to a great extent and prevent early onset of cardiac related disorders, which are prevalent in the present generation