Evaluation and assessment of adverse drug reactions at a tertiary care hospital

Abstract

Background: Improvement of patient care and safety in relation to the use of medicines with medical and paramedical interventions remains to be an important parameter. Adverse drug reactions have proved a significant problem in healthcare for a decade. The main aim of ADRs monitoring is to the promoting rational use of drugs, safe use of medicines improving patient care, improving public health. Objectives: The study aimed to determine the prevalence of ADRs in a tertiary care hospital to generating data safety of medications. Materials and Methods: The Prospective, observational study was conducted in the wards of a tertiary care Hospital. All patients were monitored for ADRs during their admission period. ADRs are a common occurrence but are often not recognized. Even if recognized, they are underreported as many physicians are unaware that all ADRs should be reported to ADR monitoring centers. Results and Discussion: Over the study period of two years, a total of 325 patients reports were monitored. The ADRs observed were higher in male patients and the highest number of ADRs were reported in the case of Sacubitril/valsartan followed by Amlodipine and in most of the cases drug is withdrawn.