Evaluating therapeutic benefits of ubrogepant via latent class models: A post hoc exploratory analysis of the ACHIEVE I and ACHIEVE II trials
Charlie J. Iaconangelo,
Daniel Serrano,
Aubrey Manack Adams
et al.
Abstract:ObjectiveTo evaluate an alternative method of defining acute treatment success in migraine by combining multiple indicators into a single dichotomous measure of success.BackgroundMigraine is characterized by a symptom complex; combining these features as a single endpoint may improve the measurement of treatment effects and better predict patient satisfaction with treatment.MethodsWe used a confirmatory latent class model (LCM) with two latent classes interpreted as treatment success and treatment failure. Poo… Show more
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