Evaluating the Impact of Preoperative Breast Magnetic Resonance Imaging on the Surgical Management of Newly Diagnosed Breast Cancers

Bilimoria, Karl Y.; Cambic, Angela; Hansen, Nora M.; Bethke, Kevin P.

doi:10.1001/archsurg.142.5.441

Cited by 132 publications

(78 citation statements)

References 25 publications

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“…Several studies reported a higher sensitivity of contrastenhanced magnetic resonance imaging (CE MRI) to detect invasive breast cancer and to visualize disease extent compared to the standard workup using conventional imaging [8][9][10][11]. These observations have led to changes in the surgical management of patients [12][13][14][15][16][17]. Preoperative breast MRI for women with known breast cancer is, however, controversial due to the increase in cost, mastectomy rate and larger excisions, without knowing the benefit in local control [18][19][20][21][22][23].…”

Section: Introductionmentioning

confidence: 99%

The impact of preoperative MRI on breast-conserving surgery of invasive cancer: a comparative cohort study

Pengel

Loo

Teertstra

et al. 2008

Breast Cancer Res Treat

109

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Section: Introductionmentioning

confidence: 99%

The impact of preoperative MRI on breast-conserving surgery of invasive cancer: a comparative cohort study

Pengel

Loo

Teertstra

et al. 2008

Breast Cancer Res Treat

109

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“…[4][5][6][7][8][9][10][11][12][13][14][15] Of the 22 malignant lesions identified only on DCE MRI, 13 (59%) lesions were invasive carcinoma and 5 (56%) lesions of the 9 DCE MRIdetected ductal carcinomas in situ were grade 3, with 1 lesion being 8 cm in size. These clinically significant lesions would have been missed if pre-operative DCE MRI had not been performed, lending some support for breast MRI in staging newly diagnosed breast cancer.…”

Section: Discussionmentioning

confidence: 99%

“…3 Numerous studies have also shown that MRI improves the detection of occult tumour foci in the ipsilateral and contralateral breasts in patients with newly diagnosed breast cancer, leading to changes in surgical planning. [4][5][6][7][8][9][10][11][12][13][14][15] Systematic reviews of the literature found that pre-operative MRI detected additional ipsilateral disease in 16-20% of patients and occult synchronous contralateral cancer in 4-5% of patients. [16][17][18] Despite the widespread use of breast MRI for pre-operative staging in recent years, this use remains controversial.…”

Section: Introductionmentioning

confidence: 99%

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

He¹,

Plaxco²,

Wei³

et al. 2016

BJR

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Objective: To compare the incremental cancer detection rate (ICDR) using bilateral whole-breast ultrasonography (BWBUS) vs dynamic contrast-enhanced MRI in patients with primary breast cancer. Methods: A retrospective database search in a single institution identified 259 patients with breast cancer diagnosed from January 2011 to August 2014 who underwent mammography, BWBUS and MRI before surgery. Patient characteristics, tumour characteristics and lesions seen on each imaging modality were recorded. The sensitivity, specificity and accuracy for each modality were calculated. ICDRs according to index tumour histology and receptor status were also evaluated. The effect of additional cancer detection on surgical planning was obtained from the medical records. Results: A total of 266 additional lesions beyond 273 index malignancies were seen on at least 1 modality, of which 121 (45%) lesions were malignant and 145 (55%) lesions were benign. MRI was significantly more sensitive than BWBUS (p 5 0.01), while BWBUS was significantly more accurate and specific than MRI (p , 0.0001). Compared with mammography, the ICDRs using BWBUS and MRI were significantly higher for oestrogen receptorpositive and triple-negative cancers, but not for human epidermal growth factor receptor 2-positive cancers. 22 additional malignant lesions in 18 patients were seen on MRI only. Surgical planning remained unchanged in 8 (44%) of those 18 patients. Conclusion: MRI was more sensitive than BWBUS, while BWBUS was more accurate and specific than MRI. MRIdetected additional malignant lesions did not change surgical planning in almost half of these patients. Advances in knowledge: BWBUS may be a cost-effective and practical tool in breast cancer staging.

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“…Routine preoperative MRI in women already diagnosed with breast cancer detects mammographically occult ipsilateral multicentric cancer in 20% women and contralateral synchronous cancer in 3-5% women. 26 …”

Section: Preoperative Hook Wire Localizationmentioning

confidence: 99%

Scope of Breast Imaging in Developing Countries

2014

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Evaluating the Impact of Preoperative Breast Magnetic Resonance Imaging on the Surgical Management of Newly Diagnosed Breast Cancers

Cited by 132 publications

References 25 publications

The impact of preoperative MRI on breast-conserving surgery of invasive cancer: a comparative cohort study

The impact of preoperative MRI on breast-conserving surgery of invasive cancer: a comparative cohort study

Incremental cancer detection using breast ultrasonographyversusbreast magnetic resonance imaging in the evaluation of newly diagnosed breast cancer patients

Scope of Breast Imaging in Developing Countries

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