Evaluating the Impact of Cryoprobe Tip Structure for Effective Cryoablation of Breast Cancer

Ahmed, Farooq; Ali, Shams Nafisa; Akter, Tanzila; Ferdous, Jannatul

doi:10.1109/becithcon54710.2021.9893681

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…To treat breast cancer with efficacy comparable to or superior to breast−conserving surgery, several thermal techniques (extreme cold or heat) have been researched and developed. Compared to surgery and other invasive treatments such as high−intensity focused ultrasound (HIFU) [ 1 ] and cryoablation [ 2 ], thermal therapies have less scarring, better tissue preservation, superior cosmesis results, faster recovery times, and lower medical costs. Non−invasive focused microwave−hyperthermia (FMHT) is an advanced method of breast−cancer treatment that uses a variety of antennas or antenna arrays to focus the power of microwaves on human malignant tissue [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Design of Ultra-Wideband Phased Array Applicator for Breast Cancer Hyperthermia Therapy

Lyu

Li²,

Li³

et al. 2023

Sensors

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Focused microwave−hyperthermia therapy has recently emerged as a key technology in the treatment of breast cancer due to non−invasive treatment. An applicator of a three−ring phased array consisting of ultra−wideband (UWB) microstrip antennas was designed for breast cancer therapy and operates at 0.915 GHz and 2.45 GHz. The proposed antenna has an ultra−wideband from 0.7 GHz to 5.5 GHz with resonant frequencies of 0.915 GHz and 2.45 GHz and dimensions of 15 × 43.5 × 1.575 mm3. The number of each ring was chosen to be 12 based on the SAR distribution and the performance indicators of tumor off−center focusing results for four different numbers of single−ring arrays. The homogeneous breast model is applied to a three−ring phased array consisting of 36 elements for focused simulation, and 1 cm3 and 2 cm3 tumors are placed in three different locations in the breast. The simulation results show that the proposed phased array has good performance and the capability to raise the temperature of different volumes of breast cancer above 42.5 °C after choosing a suitable operating frequency. The proposed applicator allows for precise treatment of tumors by selecting the appropriate operating frequency based on the size of the malignant tumor.

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Section: Introductionmentioning

confidence: 99%

Design of Ultra-Wideband Phased Array Applicator for Breast Cancer Hyperthermia Therapy

Lyu

Li²,

Li³

et al. 2023

Sensors

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“…Hyperthermia [2,3] has attracted much attention in the treatment of breast cancer, prostate cancer, liver cancer, skin cancer, etc. Considerable attention has been paid to several thermal techniques (extreme cold or heat), including cryoablation [4], radiofrequency ablation (RFA) [5], interstitial laser therapy (ILT) [6], and high-intensity focused ultrasound (HIFU) [7], which apply thermal ablation to eliminate a malignant tumor and its margins. Ongoing phase II clinical trials are evaluating the efficacy of cryoablation for low-risk breast cancer (Luminal A) as an alternative to breast surgery; however, the drawback is that there is limited control (>1.5 cm 3 ) over the size of the ablation zone near the metal probe.…”

Section: Introductionmentioning

confidence: 99%

Differential Evolution Optimization of Microwave Focused Hyperthermia Phased Array Excitation for Targeted Breast Cancer Heating

Lyu

Yang

2023

Sensors

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Microwave hyperthermia using the phased array applicator is a non-invasive treatment modality for breast cancer. Hyperthermia treatment planning (HTP) is critical to accurately treating breast cancer and avoiding damage to the patient’s healthy tissue. A global optimization algorithm, differential evolution (DE) algorithm, has been applied to optimize HTP for breast cancer and its ability to improve the treatment effect was proved by electromagnetic (EM) and thermal simulation results. DE algorithm is compared to time reversal (TR) technology, particle swarm optimization (PSO) algorithm, and genetic algorithm (GA) in HTP for breast cancer in terms of convergence rate and treatment results, such as treatment indicators and temperature parameters. The current approaches in breast cancer microwave hyperthermia still have the problem of hotspots in healthy tissue. DE enhances focused microwave energy absorption into the tumor and reduces the relative energy of healthy tissue during hyperthermia treatment. By comparing the treatment results of each objective function used in DE, the DE algorithm with hotspot to target quotient (HTQ) as the objective function has outstanding performance in HTP for breast cancer, which can increase the focused microwave energy of the tumor and decrease the damage to healthy tissue.

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Evaluating the Impact of Cryoprobe Tip Structure for Effective Cryoablation of Breast Cancer

Cited by 2 publications

References 12 publications

Design of Ultra-Wideband Phased Array Applicator for Breast Cancer Hyperthermia Therapy

Design of Ultra-Wideband Phased Array Applicator for Breast Cancer Hyperthermia Therapy

Differential Evolution Optimization of Microwave Focused Hyperthermia Phased Array Excitation for Targeted Breast Cancer Heating

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