Evaluating the effectiveness of two bovine mastitis vaccines and their influences on oxidant and antioxidant capacities of milk

Tashakkori, Niloufar; Khoramian, Babak; Moghadam, Mehran Farhoodı; Heidarpour, Mohammad; Mashayekhi, K.; Farzaneh, Nima

doi:10.1007/s11250-019-02156-x

Cited by 17 publications

(16 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mastitis vaccine research has been conducted over the past several years, but to date, developing an effective vaccine has been a challenge due to the nature of the disease and the pathogens involved [92,93]. For instance, an increased immune response may not always be beneficial in bovine mastitis unless increased immunity is followed by a decreased number of infecting pathogens, as the presence of a large number of bacteria in the presence of fighting immune cells is considered as an indication of mastitis which decreases milk quality [93]. Successful vaccination is challenging because the volume of milk present in the gland dilutes the number of immune effector cells available to fight off infection [92,93].…”

Section: Vaccinationmentioning

confidence: 99%

“…For instance, an increased immune response may not always be beneficial in bovine mastitis unless increased immunity is followed by a decreased number of infecting pathogens, as the presence of a large number of bacteria in the presence of fighting immune cells is considered as an indication of mastitis which decreases milk quality [93]. Successful vaccination is challenging because the volume of milk present in the gland dilutes the number of immune effector cells available to fight off infection [92,93]. In addition, fat and casein in the milk reduce the bactericidal abilities of the immune cells [93].…”

Section: Vaccinationmentioning

confidence: 99%

“…Successful vaccination is challenging because the volume of milk present in the gland dilutes the number of immune effector cells available to fight off infection [92,93]. In addition, fat and casein in the milk reduce the bactericidal abilities of the immune cells [93].…”

Section: Vaccinationmentioning

confidence: 99%

See 2 more Smart Citations

Antimicrobial Usage for the Management of Mastitis in the USA: Impacts on Antimicrobial Resistance and Potential Alternative Approaches

Gelalcha¹,

Agga²,

Dego³

2022

Mastitis in Dairy Cattle, Sheep and Goats

View full text Add to dashboard Cite

Mastitis is the most frequently diagnosed disease of dairy cattle responsible for the reduction in milk quantity and quality and major economic losses. Dairy farmers use antibiotics for the prevention and treatment of mastitis. Frequent antimicrobial usage (AMU) undeniably increased antimicrobial resistance (AMR) in bacteria from dairy farms. Antimicrobial-resistant bacteria (ARB) from dairy farms can spread to humans directly through contact with carrier animals or indirectly through the consumption of raw milk or undercooked meat from culled dairy cows. Indirect spread from dairy farms to humans can also be through dairy manure fertilized vegetables or run-off waters from dairy farms to the environment. The most frequently used antibiotics in dairy farms are medically important and high-priority classes of antibiotics. As a result, dairy farms are considered one of the potential reservoirs of ARB and antimicrobial resistance genes (ARGs). To mitigate the rise of ARB in dairy farms, reducing AMU by adopting one or more of alternative disease control methods such as good herd health management, selective dry-cow therapy, probiotics, and others is critically important. This chapter is a concise review of the effects of antimicrobials usage to control mastitis in dairy cattle farms and its potential impact on human health.

show abstract

Section: Vaccinationmentioning

confidence: 99%

Section: Vaccinationmentioning

confidence: 99%

See 1 more Smart Citation

Antimicrobial Usage for the Management of Mastitis in the USA: Impacts on Antimicrobial Resistance and Potential Alternative Approaches

Gelalcha¹,

Agga²,

Dego³

2022

Mastitis in Dairy Cattle, Sheep and Goats

View full text Add to dashboard Cite

show abstract

“…Some vaccines have been licensed in several countries to prevent the onset of mastitis (Tashakkori et al, 2020). A limitation of the vaccines is that the targets depend on their composition, such as S. aureus and E. coli , despite numerous pathogens being known to cause mastitis.…”

Section: Introductionmentioning

confidence: 99%

“…These bacteria are especially important, because they often infect the mammary gland shortly after drying off and before parturition, when immunosuppression of cows increases the incidence of mastitis compared with the incidence during lactation (Sordillo, 2005). Some vaccines have been licensed in several countries to prevent the onset of mastitis (Tashakkori et al, 2020). A limitation of the vaccines is that the targets depend on their composition, such as S. aureus and E. coli, despite numerous pathogens being known to cause mastitis.…”

Section: Introductionmentioning

confidence: 99%

Prevention of mastitis in multiparous dairy cows with a previous history of mastitis by oral feeding with probiotic Bacillus subtilis

Urakawa

Zhuang

Sato³

et al. 2022

Animal Science Journal

View full text Add to dashboard Cite

Mastitis is a very common inflammatory disease of the mammary gland of dairy cows, resulting in a reduction of milk production and quality. Probiotics may serve as an alternative to antibiotics to prevent mastitis, and the use of probiotics in this way may lessen the risk of antibiotic resistant bacteria developing. We investigated the effect of oral feeding of probiotic Bacillus subtilis (BS) C‐3102 strain on the onset of mastitis in dairy cows with a previous history of mastitis. BS feeding significantly decreased the incidence of mastitis, the average number of medication days and the average number of days when milk was discarded, and maintained the mean SCC in milk at a level substantially lower than the control group. BS feeding was associated with lower levels of cortisol and TBARS and increased the proportion of CD4+ T cells and CD11c+ CD172ahigh dendritic cells in the blood by flow cytometry analysis. Parturition increased the migrating frequency of granulocytes toward a milk chemoattractant cyclophilin A in the control cows, however, this was reduced by BS feeding, possibly indicating a decreased sensitivity of peripheral granulocytes to cyclophilin A. These results reveal that B. subtilis C‐3102 has potential as a probiotic and has preventative capacity against mastitis in dairy cows.

show abstract

Bovine mastitis prevention and control in the post-antibiotic era

El-Sayed

Kamel

2021

Trop Anim Health Prod

View full text Add to dashboard Cite

Evaluating the effectiveness of two bovine mastitis vaccines and their influences on oxidant and antioxidant capacities of milk

Cited by 17 publications

References 14 publications

Antimicrobial Usage for the Management of Mastitis in the USA: Impacts on Antimicrobial Resistance and Potential Alternative Approaches

Antimicrobial Usage for the Management of Mastitis in the USA: Impacts on Antimicrobial Resistance and Potential Alternative Approaches

Prevention of mastitis in multiparous dairy cows with a previous history of mastitis by oral feeding with probiotic Bacillus subtilis

Bovine mastitis prevention and control in the post-antibiotic era

Contact Info

Product

Resources

About