Evaluating the clinical and economic burden of healthcare-associated infections during hospitalization for surgery in France

Abstract

SUMMARYOver 4 million patients suffer nosocomial infections annually in the European Union. This study aimed to estimate the healthcare burden associated with healthcare-associated infections (HAIs) following surgery in France, and explore the potential impact of infection control strategies and interventions on the clinical and economic burden of disease. Data on the frequency of HAIs were gathered from the 2010 Programme de Médicalisation des Systèmes d'Information (PMSI), and cost data were taken from the 2009 Echelle Nationale de Coûts à Méthodologie Commune (ENCC). It was estimated that 3% of surgical procedures performed in 2010 in France resulted in infection, resulting in an annual cost of €57 892 715. Patients experiencing a HAI had a significantly increased mortality risk (4·15-fold) and an increased length of hospital stay (threefold). Scenario analysis in which HAI incidence following surgery was reduced by 8% (based on a study of the effectiveness of triclosan-coated sutures), suggested that, annually, 20 205 hospital days and €4 588 519 could be saved. Analyses of 20% and 30% reductions in incidence (based on an estimate of the number of preventable nosocomial infections) suggested that annual savings of €11 548 057 and €17 334 696, respectively, could be made. New infection control interventions which reduce HAI incidence during hospitalization for surgery have the potential to provide valuable cost savings to healthcare providers.

Bacteriology and risk factors associated with periprosthetic joint infection after primary total knee arthroplasty: retrospective study of 2543 cases

“…Moreover, PJI incurs considerable health care costs. [1][2][3] Therefore, multiple strategies including antibiotic prophylaxis, body exhaust systems, and laminar airflow systems have been developed to reduce the incidence of PJI. Studies have also identified modifiable risk factors ORIGINAL ARTICLE aureus was the most common causative organism.…”

Primary skin closure after damage control laparotomy

“…The International Nosocomial Infection Control Consortium, a voluntary multicentre collaborative that includes hospitals from many low‐income countries, noted that SSI rates were higher for more than half of the surgical procedures in their hospitals compared with those published by the US Centers for Disease Control and Prevention National Healthcare Safety Network. In addition, the clinical and economic burden of SSIs is well documented, regardless of geography. SSIs are associated with prolonged hospital stay, more readmissions, additional surgical procedures, prolonged antibiotic use and antimicrobial resistance, and increased health resource utilization.…”

Mixed method versus full top-down microcosting for organ recovery cost assessment in a French hospital group

“…Their use, as a medico-administrative and an economic database, respectively, allowed for carrying out previous medico-economic analyses [17]. The French College of Health Economists recommended using this medico-administrative database for health economic evaluations [18].…”