Evaluating the antioxidant activity of secondary metabolites of endophytic fungi from Hypericum perforatum L. by an electrochemical biosensor based on AuNPs/AC@CS composite

Exploring the potential of ternary nanocomposite in biosensor development

“…An electrochemical sensor for the endophytic fungi Hypericum perforatum L. was crafted from the synergy of chitosan functionalised activated carbon (AC) and gold nanoparticles [98]. The biosensor was prepared by dropping 20 μL chitosan functionalised AC solution on a glassy carbon electrode (GCE), and AuNP was electrodeposited on the electrode surface by cycling a potential from À 0.8 to 1.2 V at a scan rate of 50 mV/s using cyclic voltammetry.…”

“…GOx/SPG-AuNPs-CH/ITO Glucose/Amp 0.5-22.2 0.13 [87] AuNPs/PPy/rGO/GOD/chitosan@GCE Glucose/CV 0.2-1.2 0.1238 [88] Au/CNTs-Graphene@GCE Glucose/Amp 0.01-6.1 0.001 [89] AuNPs/rGO/g-C3 N4@Au electrode DNA/DPV 0.01-10 0.0074 [90] AuNPs/CdSQDs/CeO2 nanoprobes@GCE miRNA-182-5p/PEC 0.1-1 0.03 [91] Au@α-Fe2O3@rGO@ GCE Caffeic acid/DPV 0.019-1.869 0.0098 [92] Fe3O4/α-Fe2O3 NRs@Au@GCE Human epididymis protein/DPV 0.01-1 0.00275 [93] Fe3O4@SiO2-Au@GCE SARS-CoV-2/EIS 0.01-10 0.00478 [94] PAMAM@Au@Graphene sheets@GCE Dopamine/DPV 0.03-10 0.008 [95] 3D GF/CS-AuNPs@ microfluidic electrochemical chip Prostate specific antigen/DPV 0.01-200 0.0051 [96] Au/Graphene-CS@GCE H2O2/Amp 0.2-9.35 0.0035 [97] AuNPs/AC@CS@GCE DNA/SWV Not reported Not reported [98] DNA/AuÀ Pt/GO-chit@PGE Zidovudine/DPV 0.01-10 0.003 [99] rGOÀ Pd@Au-Thi@GCE CEA/DPV 0.01-20 0.00149 [100] rGO/Pd@Poly (2-Amino-4 chlorophenol) @GCE DNA/ DPV 0.1-0.5 0.0513 [101] Ag/TiO2/rGO@GCE Cancer antigen (CA 15-3)/ Amp 0.1-300 0.07 [102] (Th-CSÀ Ni(OH)2NPs-ERGO)@GCE Anti-p53 autoantibody/ DPV and EIS 0.1-500 & 5-150 0.001 & 0.007 [103) MXene (Ti3 C2)-rGO@Au@GCE miRNA-21/DPV 0.1-1 0.001 [104) rGO@CuONPs@Chitosan@GCE Human Serum Albumin (HSA)/ DPV 10-450 2.6 [105] rGO@MoS2-poly (3, 4-ethylene dioxythiophene)-@GCE Nitrite/DPV 0.01-1 0.0059 [106] rGO/MnFe2O4/Polyaniline@GCE Nitrite/DPV 0.05-12000 0.015 [107] rGO@silver nanowires (AgNWs)/AgNP@SPCE Dopamine, Uric acid and Estriol/DPV 0.6-50, 1-100 & 1-90 0.016, 0.58 & 0.58 [108] Cu2OÀ Cu-Au/GCE Glucose/Amp 0-4.5 1.71 [109] Ag/PPy/Cu2O@GCE Serotonin (5HT)/DPV 0.1-250 0.0124 [110] NiFe2O4/CuO/FeO-chitosan/ITO Cholesterol/DPV 50-5000 31 [111] BiIO4-WS2/CuO/ITO 5-formylcytosine (5fc)/PEC 0.05-200 0.038 [112] MoS2/WS2@PDA/ITO DNA/PEC 0.5-200 0.37 [113] CuFe PBA/MoS2/GCE CEA/DPV 1-100 0.01 [114] PMO-NiO/MoS2/SPCE Cholesterol/DPV 1-15 0.24 [115] (Th-CSÀ Ni(OH) 2 NPs-ERGO)@GCE-Thionine/chitosan/nickel hydroxide nanoparticl...…”

“… Schematic representation of constructing ds‐DNA/AuNPs/AC@CS/GCE electrochemical biosensor for evaluating the antioxidant activity of SMEF from HP L. Adapted from Elsevier (Ref. [98]). …”