Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES)

Kot, Kevin Liu; Labagnara, Kevin; Kim, Joseph I.; Loloi, Justin; Gupta, Kavita; Agalliu, Ilir; Small, Alexander

doi:10.1007/s00240-023-01423-9

Cited by 3 publications

(1 citation statement)

References 20 publications

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“…However, based on findings from more recent studies, a higher intake of vitamin C was inversely associated with the risk of stone formation. Specifically, daily intake levels between 60 and 110 mg were linked to a reduced risk (OR = 0.76; 95% CI: 0.60–0.95), as were levels above 110 mg (OR = 0.80; 95% CI: 0.66–0.97) [ 85 ]. In a comprehensive cross-sectional study, Zeng et al explored the relationship between nine common vitamins and the prevalence of kidney stones.…”

Section: Modifiable Lifestyle Factors and Habitsmentioning

confidence: 99%

The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease—A State-of-the-Art Review

Balawender,

Łuszczki,

Mazur

et al. 2024

Nutrients

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Kidney stone disease has a multifactorial etiology, and evolving dietary habits necessitate continuous updates on the impact of dietary components on lithogenesis. The relationship between diseases influenced by lifestyle, such as obesity and diabetes, and kidney stone risk underscores the need for comprehensive lifestyle analysis. Effective management of kidney stones requires a multidisciplinary approach, involving collaboration among nutritionists, urologists, nephrologists, and other healthcare professionals to address the complex interactions between diet, lifestyle, and individual susceptibility. Personalized dietary therapy, based on each patient’s unique biochemical and dietary profile, is essential and necessitates comprehensive nutritional assessments. Accurate dietary intake evaluation is best achieved through seven-day, real-time dietary records. Key factors influencing urinary risk include fluid intake, dietary protein, carbohydrates, oxalate, calcium, and sodium chloride. Personalized interventions, such as customized dietary changes based on gut microbiota, may improve stone prevention and recurrence. Current research suggests individualized guidance on alcohol intake and indicates that tea and coffee consumption might protect against urolithiasis. There is potential evidence linking tobacco use and secondhand smoke to increased kidney stone risk. The effects of vitamins and physical activity on kidney stone risk remain unresolved due to mixed evidence. For diseases influenced by lifestyle, conclusive evidence on targeted interventions for nephrolithiasis prevention is lacking, though preliminary research suggests potential benefits. Management strategies emphasize lifestyle modifications to reduce recurrence risks, support rapid recovery, and identify predisposing conditions, highlighting the importance of these changes despite inconclusive data.

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Section: Modifiable Lifestyle Factors and Habitsmentioning

confidence: 99%

The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease—A State-of-the-Art Review

Balawender,

Łuszczki,

Mazur

et al. 2024

Nutrients

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Higher oxidative balance score is associated with lower kidney stone disease in US adults: a population-based cross-sectional study

Lei,

Wen,

2024

World J Urol

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Elucidating shared biomarkers and pathways in kidney stones and diabetes: insights into novel therapeutic targets and the role of resveratrol

et al. 2023

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Background The pathogenic mechanisms shared between kidney stones and diabetes at the transcriptional level remain elusive, and the molecular mechanisms by which resveratrol exerts its protective effects against these conditions require further investigation. Methods To address these gaps in knowledge, we conducted a comprehensive analysis of microarray and RNA-seq datasets to elucidate shared biomarkers and biological pathways involved in the pathogenesis of kidney stones and diabetes. An assortment of bioinformatic approaches was employed to illuminate the common molecular markers and associated pathways, thereby contributing to the identification of innovative therapeutic targets. Further investigation into the molecular mechanisms of resveratrol in preventing these conditions was conducted using molecular docking simulation and first-principles calculations. Results The study identified 11 potential target genes associated with kidney stones and diabetes through the intersection of genes from weighted gene co-expression network analysis (WGCNA) and differentially expressed genes (DEGs) screening. Among these, Interleukin 11 (IL11) emerged as a pivotal hub gene and a potential diagnostic biomarker for both conditions, particularly in males. Expression analysis of IL11 demonstrated elevated levels in kidney stones and diabetes groups compared to controls. Additionally, IL11 exhibited correlations with specific cell types and differential expression in normal and pathological conditions. Gene set enrichment analysis (GSEA) highlighted significant disparities in biological processes, pathways, and immune signatures associated with IL11. Moreover, molecular docking simulation of resveratrol towards IL11 and a first-principles investigation of Ca adsorption on the resveratrol surface provided structural evidence for the development of resveratrol-based drugs for these conditions. Conclusions Overall, this investigation illuminates the discovery of common molecular mechanisms underlying kidney stones and diabetes, unveils potential diagnostic biomarkers, and elucidates the significance of IL11 in these conditions. It also provides insights into IL11 as a promising therapeutic target and highlights the role of resveratrol. Nonetheless, further research is warranted to enhance our understanding of IL11 targeting mechanisms and address any limitations in the study.

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Evaluating the American Urologic Association (AUA) dietary recommendations for kidney stone management using the National Health And Nutritional Examination Survey (NHANES)

Cited by 3 publications

References 20 publications

The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease—A State-of-the-Art Review

The Multidisciplinary Approach in the Management of Patients with Kidney Stone Disease—A State-of-the-Art Review

Higher oxidative balance score is associated with lower kidney stone disease in US adults: a population-based cross-sectional study

Elucidating shared biomarkers and pathways in kidney stones and diabetes: insights into novel therapeutic targets and the role of resveratrol

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