Evaluating Outcomes and Misuse in Opioid-Dependent Chronic Pancreatitis Using a State-Mandated Monitoring System

Shah, Ishani; Bocchino, Rachel L.; Yakah, William; Ahmed, Awais; Freedman, Steven D.; Kothari, Darshan; Sheth, Sunil G.

doi:10.1007/s10620-022-07459-y

Cited by 6 publications

(3 citation statements)

References 30 publications

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“…Since alcohol 3 Multivariable logistic regression analysis of anxiety, depression, and sociodemographic and clinical characteristics abuse is considered to be one of the important risk factors for increased pain and increased stone formation in CP patients [26,27], the differences in the etiology of CP between East and West and the different severity of the disease caused by it may contribute to the differences in the incidence of anxiety and depression. In addition, Shah et al found that the prevalence of opioid dependence among CP patients in the United States was 48.87%, and opioid dependence was associated with a higher incidence of anxiety and depression [28]. However, the use of opioids in China is quite conservative due to medical regulations [29].…”

Section: Discussionmentioning

confidence: 99%

Anxiety, depression, and coping styles among patients with chronic pancreatitis in East China

Zhou

Wang²,

Li³

et al. 2023

BMC Psychiatry

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Background Anxiety and depression are common psychological comorbidities in patients with chronic pancreatitis (CP). There is still a lack of epidemiological studies on anxiety and depression in Chinese CP patients. This study aimed to identify the incidence and related factor of anxiety and depression among East Chinese CP patients and explore the relationship between anxiety, depression, and coping styles. Methods This prospective observational study was conducted from June 1, 2019 to March 31, 2021 in Shanghai, China. Patient diagnosed with CP were interviewed using the sociodemographic and clinical characteristics questionnaire, Self-rating Anxiety Scale (SAS), Self-rating Depression Scale (SDS), and Coping Style Questionnaire (CSQ). Multivariate logistic regression analysis was conducted to identify the related factors of anxiety and depression. Correlation test was preformed to analyze the correlation between anxiety, depression, and coping styles. Results The incidence of anxiety and depression in East Chinese CP patients was 22.64% and 38.61%, respectively. Patients’ previous health status, level of disease coping, frequency of abdominal pain episodes, and pain severity were significantly associated with anxiety and depression. Mature coping styles (Problem solving, Seeking for help) had a positive impact on anxiety and depression, while immature coping styles (Self-blame, Fantasy, Repression, Rationalization) had negative effects on anxiety and depression. Conclusion Anxiety and depression were common in patients with CP in China. The factors identified in this study may provide references for the management of anxiety and depression in CP patients.

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Section: Discussionmentioning

confidence: 99%

Anxiety, depression, and coping styles among patients with chronic pancreatitis in East China

Zhou

Wang²,

Li³

et al. 2023

BMC Psychiatry

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“…However, the chronic use of opioid is independently associated with mental health disorders. 13 Celiac plexus block and celiac plexus neurolysis are a nonsurgical, nonnarcotic treatment method for controlling CP-related pain. 14 However, their pain-relieving effect is temporary, and they are associated with a risk of complications such as infection and neuropathy.…”

Section: Surg Ic Al and Nonsurg Ic Al Tre Atment For Cp And R Apmentioning

confidence: 99%

“…Treatment with narcotics is considered in patients with refractory pain if the abovementioned medical therapies are insufficient. However, the chronic use of opioid is independently associated with mental health disorders 13 . Celiac plexus block and celiac plexus neurolysis are a nonsurgical, nonnarcotic treatment method for controlling CP‐related pain 14 .…”

Section: Surgical and Nonsurgical Treatment For Cp And Rapmentioning

confidence: 99%

Current status of total pancreatectomy with islet autotransplantation for chronic and recurrent acute pancreatitis

Yamane,

Anazawa,

Nagai

et al. 2023

Annals of Gastroent Surgery

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Total pancreatectomy with islet autotransplantation (TPIAT) is an established and effective treatment modality for patients diagnosed with intractable chronic pancreatitis (CP) and recurrent acute pancreatitis (RAP). TPIAT primarily aims to manage debilitating pain leading to impaired quality of life among patients with CP or RAP, which can be successfully managed with medical, endoscopic, or surgical interventions. TPIAT is significantly successful in relieving pain associated with CP and improving health‐related quality of life outcomes. Furthermore, the complete loss of pancreatic endocrine function attributed to total pancreatectomy (TP) can be compensated by autologous islet transplantation (IAT). Patients receiving IAT can achieve insulin independence or can be less dependent on exogenous insulin compared with those receiving TP alone. Historically, TPIAT has been mainly used in the United States, and its outcomes have been improving due to technological advancements. Despite some challenges, TPIAT can be a promising treatment for patients with CP‐related intractable pain. Thus far, TPIAT is not commonly performed in Japan. Nevertheless, it may improve health‐related quality of life in Japanese patients with CP, similar to Western patients. This review article aimed to provide an overview of the indications, related procedures, and outcomes of TPIAT and to discuss future prospects in Japan.

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Adjunctive Therapy in Chronic Pancreatitis

Phillips

2023

The Pancreas

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Evaluating Outcomes and Misuse in Opioid-Dependent Chronic Pancreatitis Using a State-Mandated Monitoring System

Cited by 6 publications

References 30 publications

Anxiety, depression, and coping styles among patients with chronic pancreatitis in East China

Anxiety, depression, and coping styles among patients with chronic pancreatitis in East China

Current status of total pancreatectomy with islet autotransplantation for chronic and recurrent acute pancreatitis

Adjunctive Therapy in Chronic Pancreatitis

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