“…After long years of use, it has come to the fore with an important side effect defined in recent years: "postoperative delirium". 2,8 It is said that 57% of patients are affected by delirium and this causes longer ICU and hospital stays after cardiac surgery. 8 With an increasing demand for intensive cardiovascular and ventilatory support during the immediate postoperative period, the "fast-tracking cardiac anesthesia" term has emerged.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, midazolam has been shown to cause a high rate of postoperative delirium, and prolonged ICU stays in cardiac surgery patients. 2 Fast track and balanced anesthesia protocols have been developed in years for all these reasons. The balanced anesthesia methods are provided with a sedative-hypnotic agent with a low side-effect profile, as well as opioids with a short duration of action and volatile anesthetics.…”
Section: The Effects Of Conventional and Balanced Anesthesia Protocol...mentioning
Because the compromised circulatory system is less tolerant of depression, anesthesia induction in patients with heart disease is generally problematic.Attenuating sympathetic activity to noxious stimuli such as laryngoscopy, intubation, and the surgical incision is one of the primary goals of cardiac
“…After long years of use, it has come to the fore with an important side effect defined in recent years: "postoperative delirium". 2,8 It is said that 57% of patients are affected by delirium and this causes longer ICU and hospital stays after cardiac surgery. 8 With an increasing demand for intensive cardiovascular and ventilatory support during the immediate postoperative period, the "fast-tracking cardiac anesthesia" term has emerged.…”
Section: Discussionmentioning
confidence: 99%
“…In addition, midazolam has been shown to cause a high rate of postoperative delirium, and prolonged ICU stays in cardiac surgery patients. 2 Fast track and balanced anesthesia protocols have been developed in years for all these reasons. The balanced anesthesia methods are provided with a sedative-hypnotic agent with a low side-effect profile, as well as opioids with a short duration of action and volatile anesthetics.…”
Section: The Effects Of Conventional and Balanced Anesthesia Protocol...mentioning
Because the compromised circulatory system is less tolerant of depression, anesthesia induction in patients with heart disease is generally problematic.Attenuating sympathetic activity to noxious stimuli such as laryngoscopy, intubation, and the surgical incision is one of the primary goals of cardiac
“…Delirious patients often remove intubation and infusion tubes from the body, which seriously threatens the safety of patients' lives. For the occurrence of postoperative delirium, current research has confirmed many factors including major bleeding during surgery, hemodynamic instability, and the patient's history of cerebrovascular disease [47][48][49][50][51] . However, there is still a lack of a systematic and effective prediction system, thence it is of great significance to explore and study the prediction scoring system for delirium following OPCABG.…”
Objective To determine the predictive value of surgical Apgar score on
delirium postoperatively following OPCABG. Method Intraoperative
anesthesia data of patients underwent OPCABG during the period of
January 2012 and December 2019 were reviewed and SAS score of each
patient was calculated. Relationship between SAS score and postoperative
occurrence of delirium were analyzed to determine the underlying
mechanism. Results There are a total of 436 patients included with a
mean age of 62.8±13.8 and 61.2±16.8 in each group. Patients in Delirium
group had significantly higher incidence of heart failure (P=0.043)
preoperatively in the Delirium group. No significant difference was
observed referring to ASA PS III (P=0.102) and no significant difference
was observed in duration of the surgery and anesthesia. Also no
significant differences was observed as to dexmedetomidine and propofol
use (P=0.256, P=0.278). The mean SAS score was in 4.2±0.8, 7.8±1.2 in
two groups respectively (P<0.001) and 96(22.02%) postoperative
delirium events were recorded. Patients in Delirium group had much more
EBL (P<0.001) while LHR (P=102) showed no significant statistical
difference between two groups. Univariate and multivariate regression
analysis showed that the intraoperative SAS score was significant
predictors of delirium following OPCABG (P<0.001; P<0.001). After
adjustment for other clinical predictors, the addition of SAS also
improved and the area under the curve to predict delirium was 0.934
(95%CI, 0.907-0.960, P<0.001). Conclusions Intraoperative SAS score is
associated with postoperatively following OPCABG and SAS score may be a
valuable component to improve preoperative risk stratification of
delirium among patient under OPCABG.
“…El DPO es una de las complicaciones frecuentes de la cirugía. Ocurre hasta en un 65% de los pacientes de todas las edades, siendo este porcentaje dependiente del tipo de cirugía (mayor incidencia en cirugías mayores y de emergencia frente a las cirugías menores y electivas) y del procedimiento al cual se va a someter el paciente, así como de la edad de este, ya que el DPO es más frecuente en adultos mayores (> 65 años), lo cual es un gran problema sanitario, debido a que más de un tercio de las cirugías realizadas en pacientes ingresados en un centro hospitalario ocurren en este grupo etario (1,7,(12)(13)(14)(15). Los adultos mayores, al ser sometidos a cirugía, se encuentran en un riesgo del 15-53% de presentar DPO; dicho porcentaje aumenta hasta un 70-87% si el paciente requiere ser admitido en una unidad de cuidados intensivos (1,3,4,9).…”
Section: Epidemiologíaunclassified
“…Igualmente, el uso de dexmedetomidina, la restricción del uso de medicamentos anticolinérgicos, una analgesia óptima y evitar la polifarmacia, han demostrado una reducción en la incidencia del DPO (1,4,5,7,11,(13)(14)(15).…”
El delirium postoperatorio, es la causa más común de complicaciones posterior a cirugía en aquellos pacientes que superan los 65 años. Se manifiesta como una disfunción cognitiva y de la atención de forma aguda, caracterizado por ser transitoria y fluctuante. Estas manifestaciones se observan en horas o días posterior a una intervención quirúrgica. En los últimos años ha recobrado gran interés, en parte por el aumento en la expectativa de vida en el adulto mayor, promoviendo así un incremento en la incidencia del delirium postperatorio, motivo por el cual ha sido tema de estudio, aunque su fisiopatología aún es poco clara. Su prevención es clave ya que la evidencia farmacológica en el manejo una vez instaurado es insuficiente; además, un 30-40% de los casos pueden ser prevenidos, esto al darse un abordaje temprano en la corrección de factores predisponentes modificables, razón por la cual es importante un entrenamiento adecuado del personal de salud implicado en la atención del paciente.
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