Evaluating HIV/AIDS Programme within South African Universities

Gobind, Jenni; Ukpere, Wilfred I.

doi:10.5901/mjss.2014.v5n3p346

Cited by 4 publications

(2 citation statements)

References 4 publications

(5 reference statements)

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“…HIV became a public health concern, demanding global health development in the year 1981 (Montagnier 2002, Girard, Osmanov et al 2006. HIV could get infected by the transfer of pre-ejaculate which is the life-threatening infection and eventually weakens the body defences by destroying certain types of white blood cells (Hawkins, Blott et al 2005, Checkley, Luttge et al 2011, Gobind 2014. Thus, every year the number of people dies from AIDS-related causes and it is getting declined from 2.3 million people to 1.6 million between the years 2005 to 2012.…”

Section: Introduction:-mentioning

confidence: 99%

Next Generation Sequence Analysis of Sequences From Sra File of Hiv-1 Envelope Protein.

Sinha¹,

Saho²,

Rana³

et al. 2018

IJAR

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Section: Introduction:-mentioning

confidence: 99%

Next Generation Sequence Analysis of Sequences From Sra File of Hiv-1 Envelope Protein.

Sinha¹,

Saho²,

Rana³

et al. 2018

IJAR

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“…These conditions constitute a major health problem worldwide, particularly in Southern Africa where an estimated 22.9 million people in the region are living with HIV; this accounts for approximately two-thirds of the world total (Geldmacher et al, 2012). In South Africa, HIV/ AIDS is a prominent health concern, and 310,000 individuals died from this disease in 2009 (Gobind and Ukpere, 2014). Most untreated people infected with HIV-1 eventually develop AIDS and die from opportunistic infections (Migueles and Connors, 2010).…”

Section: Introductionmentioning

confidence: 99%

Interleukin-7 receptor gene polymorphism at +1237 locus and its effect on susceptibility to opportunistic infections among HIV and AIDS patients in Limpopo Province, South Africa

2014

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ABSTRACT. Over the past decade, an increasing number of studies have demonstrated correlations between host genetics and susceptibility to diseases. However, few studies have investigated the effects of host genetics on the occurrence of opportunistic infections among human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) patients. In the present study, the frequency of the interleukin (IL)-7Rα +1237 A/G single nucleotide polymorphisms was determined in relation to opportunistic infection occurrence among HIV and AIDS patients in the Vhembe District. Demographic, clinical, and socioeconomic status data were collected from patients using a structured questionnaire. Genomic DNA was extracted from mouthwash samples using the QIAmp Blood Mini Kit. Genotyping of the IL-7Rα +1237 gene was conducted using a sequence-specific polymerase chain reaction method. We found that the IL-7Rα +1237 genotype distribution in our study population differed from those in European populations with a predominance of the A/G genotype. Individuals carrying the A/G genotype primarily suffered from chest pain (χ 2 = 5.016, P = 0.025), while individuals carrying the G/G genotype were protected from chest pain but had a higher prevalence of sexually transmitted disease (23 vs 16.9%); however, the difference was not statistically significant (P = 0.435). Individuals carrying the A/A genotype were more susceptible to diarrhea (32 vs 13.6%) (P = 0.034). Our data will support gene therapy and may be used to modify the course of diseases among HIV patients as well as the general population. Further studies using larger populations are needed to confirm these hypotheses.

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HIV/AIDS workplace policy addressing epidemic drivers through workplace programs

Chatora

Chibanda²,

Kampata

et al. 2018

BMC Public Health

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BackgroundHIV workplace policies have become an important tool in addressing the HIV Pandemic in Sub-Saharan Africa. In Zambia, the National AIDS Council has been advocating for establishing of HIV/AIDS workplace policies to interested companies, however no formal evaluation has been done to assess uptake and implementation. The study aimed to establish the existence of HIV/AIDS policies and programs in the private sector and to understand implementation factors and experiences in addressing HIV epidemic drivers through these programs.MethodsA mixed method assessment of the availability of policies was conducted in 128 randomly selected member companies of Zambia Federation of Employers in Lusaka. Categorized variables were analysed on Policy and programs using Stata version 12.0 for associations: Concurrently, 28 in-depth interviews were conducted on purposively sampled implementers. Qualitative results were analysed thematically before integrating them with qualitative findings.ResultsPolicies were found in 47/128 (36.72%) workplaces and the private sector accounted for 34/47 (72.34%) of all workplaces with a policy. Programs were available in 56/128 (43.75%) workplaces. The availability of policy was 2.7 times more likely to occur with increased size of a workplace, P value = 0.0001, (P < 0.05). Management support was 0.253 times more likely to occur in workplaces with policy, P value = 0.013, (P < 0.05) compared to those without. Having a specific budget for programs was 0.23 times more likely to occur in workplaces with a policy (P < 0.05) than those without a policy. Implementation was hindered by reduced funding, lack of time, sensitisation and lack of monitoring/evaluation systems.HIV awareness (56/56, 100%) and HIV/AIDS/Stigma (47/56, 83.93%) were the most addressed epidemic drivers through programs while Mother to Child Transmission (30/56 53.57%) and Males having sex with males were the least addressed (18/56, 32.14%).ConclusionHIV/AIDS policies exist in the private sector at a very low proportion but policy translation was very high suggesting that workplaces with polices are likely to implement programs. The eradication of HIV/AIDS by 2030, requires addressing epidemic drivers with a focus on marginalised populations, gender integration, a wellness and rights based approach within the context of the legal framework.

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Evaluating HIV/AIDS Programme within South African Universities

Abstract: This paper presents the occasion to consider the need and benefit of evaluating HIV/AIDS programmes within

Cited by 4 publications

References 4 publications

Next Generation Sequence Analysis of Sequences From Sra File of Hiv-1 Envelope Protein.

Next Generation Sequence Analysis of Sequences From Sra File of Hiv-1 Envelope Protein.

Interleukin-7 receptor gene polymorphism at +1237 locus and its effect on susceptibility to opportunistic infections among HIV and AIDS patients in Limpopo Province, South Africa

HIV/AIDS workplace policy addressing epidemic drivers through workplace programs

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