Home health (HH) is considered by many to be complementary to existing disease management (DM) programs, or even suitable as a stand-alone DM intervention. The advantage is thought to be with the face-to-face interaction, in contrast to the standard DM telephonic interview. However, much of the literature appears to indicate that telecommunication is as successful as face-toface contact (typically referred to as "usual care") for administering health surveys, providing counseling, changing health behaviors, and monitoring physiologic functioning. Given the desire to expand into the area of DM, HH agencies will need to identify and demonstrate areas in which they have a clinical and competitive edge over traditional DM models. This article describes and provides examples of three research designs that may assist the HH industry in evaluating their effectiveness in delivering DM services: the randomized controlled trial, the regression-discontinuity design, and casecontrol matching on the propensity score.H ome health (HH) is considered by many to be complementary to existing disease management (DM) programs, or even suitable as a stand-alone DM intervention. The prevailing thought is that HH holds an advantage over traditional DM telephonic interventions because of the face-to-face contact with patients. During the home visit, agents conduct a comprehensive assessment of the patient's living conditions and provide an objective appraisal of their functional status (physical and mental). In addition, HH caregivers identify and remove barriers and environmental irritants and ensure that patients correctly follow their treatment regimens. Taken at face value, it appears that these activities cannot be adequately replicated by a telephone call.To make a business case for HH as a suitable addition to existing DM interventions or as an alternative DM model altogether, it must first prove to be at least as effective in the delivery of DM interventions as well as being more cost-effective than standard DM methods. While telephonic and electronic communications can reach hundreds of individuals daily at relatively low cost, HH is subject to time and personnel constraints. The question is whether these fewer HH visits result in better results than their telephonic counterparts.The results gleaned from the health services research literature poses uncertainties about the advantages of face-to-face interactions over that of telecommunicating with patients.Several studies have demonstrated that there is no significant difference in how participants respond to health surveys when administered face-to-face versus telephonically