In the stage of business English translation teaching, the lack of integration of objective needs leads to the difficulty in achieving the ideal teaching effect. Therefore, the research on business English translation teaching under the situation of economic integration is proposed. For the teaching preparation, the requirements of the actual situation of business English translation for specific translation and the way of creating the situation are fully considered in the form of economic integration. The situational construction of the teaching process is realized from the perspectives of teachers' ideology and classroom situation materials; For the links in the teaching course, the situational teaching method with the attribute of "knowledge and action interaction" is constructed. By guiding students to gradually participate in the real situational activities with the characteristics of economic integration, the progressive teaching method from the periphery to the core is designed according to the three measures of new course introduction, active atmosphere and cognitive strengthening. In the test results, students' academic level and learning investment are at a high level, and good teaching results have been achieved.