Evaluating a new generation of wearable high-density diffuse optical tomography (HD-DOT) technology via retinotopic mapping in the adult brain

Abstract

We investigated the performance of a novel HD-DOT system by replicating a series of classic visual stimulation paradigms. Haemodynamic response functions and cortical activation maps replicated the results obtained with larger fibre-based systems.

Flexible-circuit-based 3-D aware modular optical brain imaging system for high-density measurements in natural settings

“…1 In response to this, fNIRS devices featuring improved wearability and portability have been actively developed over the past decade and deployed in both research and clinical settings. 30 In par-ticular, the rapid rise of modular fNIRS architectures, 31,32 alongside a diverse range of lightweight and wearable fNIRS instruments, [33][34][35][36][37][38][39] represents a promising step towards extending fNIRS-based brain monitoring to address the aforementioned challenges. Modular fNIRS systems are wearable probes comprised of repeating source and detector circuits called modules.…”

“…Modular fNIRS architectures with the ability to measure from both intra- and inter-module (optodes on different modules) source-detector (SD) pairs further improve spatial sampling density and overlapping channels, which have been shown to enhance both spatial resolution and depth specificity. 38, 42 However, compared to traditional “monolithic” fNIRS systems, modular headgear require additional considerations, including optode layout design and modular connectivity, to optimize measurement coverage. Our group has recently released an open-source toolbox specifically addressing this need.…”

“…37, 53 More recent solutions leveraging photogrammetry offer greater portability and constant sampling over time, but still require a set of external cameras that restrict mobility to areas within the cameras’ field of view. 38, 52 Integrating automated, real-time measurements of 3-D optode positions into a wearable fNIRS system would further assist motion correction and advance tomographic fNIRS to main-stream use.…”