EUS-guided gastroenterostomy is comparable to enteral stenting with fewer re-interventions in malignant gastric outlet obstruction

Abstract

EUS-GE may be ideal for malignant GOO with comparable effectiveness and safety to ES while being associated with fewer symptom recurrence and requirements for re-intervention.

Lumen‐apposing metal stents for endoscopic ultrasonography‐guided interventions

“…Although no mortality has been reported, adverse events such as peritonitis and bleeding have been reported. When compared to enteral stenting, the rates of reintervention for stent dysfunction appears to be lower (6.1% vs 30.3%) for patients undergoing EUS‐guided gastroenteric anastomosis …”

“…When compared to enteral stenting, the rates of reintervention for stent dysfunction appears to be lower (6.1% vs 30.3%) for patients undergoing EUS-guided gastroenteric anastomosis. 22,23 Altered surgical anatomy…”

Novel diagnostic and therapeutic modalities using endoscopic ultrasound in pancreatic disease

“…102 paring enteral stenting with EUS-GE revealed comparable clinical success, with 83.3% in the EUS-GE arm and 69.9% in the enteral stent cohort (P = 0.2). 103 Most notably, those undergoing EUS-GE had a lower rate of stent obstruction (3.3% EUS-GE vs 26.9%) or need for re-intervention (3.3% vs 46.2% enteral stent). 103 Celiac plexus neurolysis and celiac ganglion neurolysis…”

“…103 Most notably, those undergoing EUS-GE had a lower rate of stent obstruction (3.3% EUS-GE vs 26.9%) or need for re-intervention (3.3% vs 46.2% enteral stent). 103 Celiac plexus neurolysis and celiac ganglion neurolysis…”

Endoscopic jejunojejunostomy by use of a lumen-apposing self-expandable metal stent for treatment of obstructed efferent loop after subtotal gastrectomy with Roux-en-Y-reconstruction

“…EUS-guided interenteric anastomosis has been described mainly in patients with malignant gastric outlet obstruction, with high technical and clinical success rates 1, 2, 3. In comparison with enteral stenting, EUS-guided gastroenterostomy (GE) showed comparable safety and fewer symptom recurrences 4 . Another recently published study comparing endoscopic GE versus surgical GE showed noninferiority of endoscopic GE in terms of clinical success, and there was a trend toward fewer adverse events 5 …”