EUS elastography for the characterization of solid pancreatic masses

Iglesias‐García, Julio; Lariño‐Noia, José; Abdulkader, Ihab; Forteza, Jerónimo; Domínguez‐Muñoz, Enrique

doi:10.1016/j.gie.2009.05.011

Cited by 169 publications

(117 citation statements)

References 29 publications

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“…Iglesias Garcia et al [56] subjected 77 ductal adeno carcinomas, 42 tumor forming pancreatitis, and 10 endocrine tumors, and classified them according to the combination of the dominant color within color map (blue or green) and the homogeneity of color map (homogeneous or heterogeneous). When the combination of ''green'' and ''heterogeneous'' were determined as benign tumor forming pancreatitis, ''blue'' and ''homogeneous'' were determined as endocrine tumor, and ''blue'' and ''heterogeneous'' were determined as ductal adenocarcinoma, sensitivity, specificity, PPV, and NPV were 100%, 85.5%, 90.7%, and 100%, respectively.…”

Section: Eus-elastography -Strain Elastographymentioning

confidence: 99%

“…A recent study reported that EUS elastography could predict pancreatic exocrine dysfunction in patients with chronic pancreatitis [65] . Iglesias Garcia et al [56] hypothesized that pancreatic exocrine function was depend on the grade of pancreatic fibrosis, and measured strain ratio in 115 patients with chronic pancreatitis. They reported that there was significant correlation between strain ratio and pancreatic exocrine dysfunction evaluated by 13 C mixed triglyceride breath test.…”

Section: Eus-elastography -Strain Elastographymentioning

confidence: 99%

See 1 more Smart Citation

Elastography for the pancreas: Current status and future perspective

Kawada¹,

Tanaka²

2016

WJG

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Elastography for the pancreas can be performed by either ultrasound or endoscopic ultrasound (EUS). There are two types of pancreatic elastographies based on different principles, which are strain elastography and shear wave elastography. The stiffness of tissue is estimated by measuring the grade of strain generated by external pressure in the former, whereas it is estimated by measuring propagation speed of shear wave, the transverse wave, generated by acoustic radiation impulse (ARFI) in the latter. Strain elastography is difficult to perform when the probe, the pancreas and the aorta are not located in line. Accordingly, a fine elastogram can be easily obtained in the pancreatic body but not in the pancreatic head and tail. In contrast, shear wave elastography can be easily performed in the entire pancreas because ARFI can be emitted to wherever desired. However, shear wave elastography cannot be performed by EUS to date. Recently, clinical guidelines for elastography specialized in the pancreas were published from Japanese Society of Medical Ultrasonics. The guidelines show us technical knacks of performing elastography for the pancreas. Core tip: Elastography for the pancreas had been considered to be difficult to perform with adequate accuracy and reproducibility because the pancreas is a small organ located deep in center of the human body. This review introduces the recent innovation of elastography for the pancreas, and makes recommendations on how to use various elastographic modalities for the pancreas. The review also shows us what we can know by performing elastography for the pancreas. Elastography may be a promising imaging modality for differential diagnosis between malignant and benign pancreatic tumors, for early diagnosis of chronic pancreatitis, and for identifying high-risk patients for pancreatic cancer. TOPIC HIGHLIGHTKawada N, Tanaka S. Elastography for the pancreas: Current status and future perspective.

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Section: Eus-elastography -Strain Elastographymentioning

confidence: 99%

Section: Eus-elastography -Strain Elastographymentioning

confidence: 99%

Elastography for the pancreas: Current status and future perspective

Kawada¹,

Tanaka²

2016

WJG

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“…The blue aspect of pancreatic adenocarcinoma is on elastography due to hard desmoplastic tissue, while the soft normal tissue is red [77]. Based on the elastography pattern, the sensitivity and specificity for differentiation of benign and malignant pancreatic lesions were 92.3% and 80.0% respectively, compared to 92.3% and 68.9% for the conventional B-mode images [78], and the overall accuracy for diagnosis of malignancy was 94% [79]. The hue histogram analysis of elastographic images differentiated malignant from benign nodules (cut-off point: 175) with sensitivity, specificity, and accuracy of 91.4%, 87.9%, and 89.7% respectively [80,81].…”

Section: Elastographymentioning

confidence: 99%

Endoscopic Ultrasound in Pancreatic Cancer: The New Perspective

Seicean¹

2014

Pancreatic Cancer - Insights Into Molecular Mechanisms and Novel Approaches to Early Detection and Treatment

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“…Sensitivity, specificity and overall accuracy for the diagnosis of malignancy were 100%, 85.5% and 94% respectively. (Iglesias-Garcia et al, 2009) A Japanese group investigated the usefulness of EUS combined with contrast enhancement in the preoperative localization of pancreatic endocrine tumors (PET) and the differentiation between malignant and benign PETs. (Ishikawa et al, 2010) This group retrospectively studied 62 pathologically confirmed PETs found in 41 patients who had undergone EUS, multiphasic multidetector computed tomography (MDCT) and transabdominal ultrasound (US).…”

Section: Diagnosis and Stagingmentioning

confidence: 99%