European Scleroderma Study Group to define disease activity criteria for systemic sclerosis. IV. Assessment of skin thickening by modified Rodnan skin score

Long-term follow-up results after autologous haematopoietic stem cell transplantation for severe systemic sclerosis

“…The cohort of patients studied represented a group with SSc and poor prognosis, as assessed by their initial high mRSS, the number of patients with lung disease and the presence of anti-topoisomerase auto antibodies 6 – 9 29 – 39. The treatment regimen, as well as clinical follow-up after transplantation employed in the three hospitals were similar.…”

Association of C‐reactive protein with high disease activity in systemic sclerosis: Results from the Canadian Scleroderma Research Group

“…ESR was measured by the Westergren method (mm/hour) and was considered high when Ͼ20 mm/hour. Mean CRP concentrations (mg/liter) and the prevalence of elevated CRP levels in each disease subset were studied and associations with clinical parameters determined, including skin score measured by the modified Rodnan skin score (MRSS), estimated systolic pulmonary artery pressure (PAP) measured by transthoracic echocardiograms, pulmonary function tests (PFTs), ILD determined by chest radiographs and high-resolution computerized tomography (HRCT) of the chest, incidence of SRC, existence of arthritis determined by either tender joint count (TJC) or swollen joint count (SJC), tendon friction rubs, Scleroderma Disease Activity Score (SDAS) adapted from the European Scleroderma Study Group (EScSG) whole series activity index (33)(34)(35)(36), Scleroderma Disease Severity Score (SDSS) adapted from Medsger et al (37), and Health Assessment Questionnaire (HAQ) disability index (DI).…”

Autoanticorpos em esclerose sistêmica e sua correlação com as manifestações clínicas da doença em pacientes do Centro-Oeste do Brasil

“…O tempo entre as entrevistas foi de seis meses. Na primeira consulta foram colhidos dados demográficos e clínicos, incluindo tempo de doença, ano de diagnóstico, escore cutâneo de Rodnan modificado, 25 O sHAQ é uma medida de função na ES, ferramenta útil para a avaliação de deficiência física funcional 29 e do impacto da doença no bem estar físico e mental dos pacientes. 30 Objetivou-se correlacionar se o índice de incapacidade aferido pelo sHAQ seria maior em um dos três grupos de pacientes com autoanticorpos específicos (ACA, anti-SCL70 e anti-POL3).…”