European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB): An Update on the Pediatric CEUS Registry on Behalf of the “EFSUMB Pediatric CEUS Registry Working Group”

Dietrich, Christoph F.; Augustinienė, Rasa; Batko, Tomasz; Cantisani, Vito; Čekuolis, Andrius; Deganello, Annamaria; Ye, Dong; Franke, Doris; Harkányi, Z; Humphries, Paul; Jędrzejczyk, Maciej; Jüngert, Jörg; Kinkel, Horst; Koller, O; Kosiak, Wojciech; Kunze, Christian; Ljutikov, Anoushka; Mądzik, Jarosław; Mentzel, Hans‐Joachim; Piskunowicz, Maciej; Rafailidis, Vasileios; Schreiber-Dietrich, Dagmar; Sellars, Maria E.; Stenzel, Martin; Taut, Heike; Yusuf, Gibran Timothy; Sidhu, Paul S.

doi:10.1055/a-1345-3626

Cited by 16 publications

(14 citation statements)

References 80 publications

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“…The possible differential diagnostic option in children with focal renal infection, particularly in the early stage of abscess formation, is Wilms tumour, which has a more non-homogenous hyperenhancement of tumour tissue, usually with multiple non-enhanced areas of necrosis, various sizes and shapes. 9–11 A focal nephritis has to be differentiated from renal cell carcinoma which is hypoenhanced, but has fast washout, while in inflammatory lesions there is slow washout on delayed images. 7 On the other hand, CEUS can exclude focal renal infection by diagnosing pseudolesion, which has a similar enhancement pattern as normal kidney parenchyma, and direct the investigation searching for other infectious foci.…”

Section: Discussionmentioning

confidence: 99%

Contrast-enhanced ultrasound in detection and follow-up of focal renal infections in children

Pšeničny

Glušič

Pokorn

et al. 2022

BJR

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Objective: Focal renal infections in children have to be diagnosed early in order to enable an appropriate antibiotic treatment. The purpose of this paper was to investigate the efficacy and clinical utility of intravenous renal contrast-enhanced ultrasound (CEUS) as an alternative imaging method for the diagnosis and follow-up of focal renal infections in children. Methods: Fourteen children aged from 6 months to 17 years (mean 6.5 years) in whom focal renal infection was suspected were included in this retrospective study. All data were obtained from medical and imaging records of the patients. Results: CEUS was performed for the diagnosis in all fourteen children and then also for follow-up in seven children with renal abscess. In three children enhancement pattern was concordant with focal nephritis and in four children CEUS excluded focal renal infection and the diagnosis of pseudolesion was confirmed. Conclusions: Renal CEUS was proven to be an efficient and self-sufficient imaging in diagnosis and further follow-up of focal renal infections in children. CEUS patterns of focal renal infections are described as well as relevant CEUS enhancement patterns important for differential diagnosis. Renal abscess follow-up algorithm with CEUS is suggested. Advances in knowledge: All clinically relevant imaging data was obtained by CEUS and no other imaging was necessary for the diagnosis and follow-up.

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Section: Discussionmentioning

confidence: 99%

Contrast-enhanced ultrasound in detection and follow-up of focal renal infections in children

Pšeničny

Glušič

Pokorn

et al. 2022

BJR

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“…Liver incidentalomas are commonly encountered with a reported frequency of up to 33% of radiological studies and 50% of autopsies in adult patients [ 11 , 12 ], but they are rarely reported in children. The reasons are manifold and have been discussed in detail elsewhere [ 13 , 14 , 15 , 16 , 17 , 18 ].…”

Section: Definitionmentioning

confidence: 99%

“…The most important indications for using CEUS include: the characterization of indeterminate focal liver lesions using conventional B-mode ultrasound, computed tomography and in staging, and follow-up of previously known focal liver lesions (FLL). The latter includes pediatric patients with known cancer, patients who are under a surveillance program for chronic liver disease or other conditions that predispose them to malignancy [ 16 , 17 , 19 ], and patients who have undergone interventional procedures (e.g., post chemotherapy, or ablation) [ 20 , 21 , 22 , 23 , 24 ].…”

Section: Definitionmentioning

confidence: 99%

Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Čekuolis

Schreiber-Dietrich

Augustinienė

et al. 2023

Cancers

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The World Federation for Ultrasound in Medicine and Biology (WFUMB) is addressing the issue of incidental findings (IFs) with a series of publications entitled “Incidental imaging findings—the role of ultrasound”. IFs in the liver of newborns and children are rare and much less commonly encountered than in adults; as a result, they are relatively much more frequently malignant and life-threatening, even when they are of benign histology. Conventional B-mode ultrasound is the well-established first line imaging modality for the assessment of liver pathology in pediatric patients. US technological advances, resulting in image quality improvement, contrast-enhanced ultrasound (CEUS), liver elastography and quantification tools for steatosis have expanded the use of ultrasound technology in daily practice. The following overview is intended to illustrate incidentally detected liver pathology covering all pediatric ages. It aims to aid the examiner in establishing the final diagnosis. Management of incidentally detected focal liver lesions (FLL) needs to take into account the diagnostic accuracy of each imaging modality, the patient’s safety issues (including ionizing radiation and nephrotoxic contrast agents), the delay in diagnosis, the psychological burden on the patient and the cost for the healthcare system. Moreover, this paper should help the pediatric clinician and ultrasound practitioner to decide which pathologies need no further investigation, which ones require interval imaging and which cases require further and immediate diagnostic procedures.

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“…Microbubble contrast-enhanced ultrasound (CEUS) is a well-established safe, low-cost, and efficient imaging modality [9][10][11][12][13][14]. Microbubbles of ultrasound contrast agents (UCA) remain intravascular without diffusing into the interstitial space and are easily visible compared to the adjacent tissue, thus improving visibility of very small vascular structures.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Feasibility and Safety of Contrast-Enhanced Ultrasound of the Neonatal Brain: A Prospective Study Using MRI as the Reference Standard

Squires

Beluk

Lee

et al. 2022

American Journal of Roentgenology

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The publication of this Accepted Manuscript is provided to give early visibility to the contents of the article, which will undergo additional copyediting, typesetting, and review before it is published in its final form. During the production process, errors may be discovered that could affect the content of the Accepted Manuscript. All legal disclaimers that apply to the journal pertain. The reader is cautioned to consult the definitive version of record before relying on the contents of this document.

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European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB): An Update on the Pediatric CEUS Registry on Behalf of the “EFSUMB Pediatric CEUS Registry Working Group”

Cited by 16 publications

References 80 publications

Contrast-enhanced ultrasound in detection and follow-up of focal renal infections in children

Contrast-enhanced ultrasound in detection and follow-up of focal renal infections in children

Incidental Findings in Pediatric Patients: How to Manage Liver Incidentaloma in Pediatric Patients

Feasibility and Safety of Contrast-Enhanced Ultrasound of the Neonatal Brain: A Prospective Study Using MRI as the Reference Standard

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