Eucalyptus oil poisoning

Kumar, K. Jagadish; Sonnathi, Sandeep; Anitha, C.; Santhoshkumar, M.

doi:10.4103/0971-6580.172259

Cited by 21 publications

(18 citation statements)

References 4 publications

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“…5 A case of status epilepticus has been documented after 10 min of ingestion of 10 ml of EO in a 6-year-old boy. 6 Occurrence of seizures after dermal application of an EO head lice preparation in a 4-year-old girl has also been recently reported. 7 However, in our cohort we had mostly adult patients, and the mode of exposure was inhalation, and seizures developed after 2-5 min.…”

Section: Discussionmentioning

confidence: 89%

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Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

Mathew

Kamath

Kumar³

et al. 2017

Epilepsia Open

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SummaryEucalyptus oil (EO) is an essential oil that is widely used across the globe as an over‐the‐counter remedy for common ailments. EO‐induced seizure (EOIS) has not been recognized as an entity, and physicians rarely ask the history of exposure to eucalyptus oil when seeing a patient with first episode of seizure. Here we report 10 cases of EO inhalation–induced seizures seen over the past 2 years in three tertiary care hospitals. Eight patients had GTCS and two had CPS. We aim to raise awareness of seizures induced by exposure to eucalyptus oil.

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Section: Discussionmentioning

confidence: 89%

“…Seizure has been reported 9 hours after ingestion in a 4‐year‐old child . A case of status epilepticus has been documented after 10 min of ingestion of 10 ml of EO in a 6‐year‐old boy . Occurrence of seizures after dermal application of an EO head lice preparation in a 4‐year‐old girl has also been recently reported .…”

Section: Discussionmentioning

confidence: 93%

Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

Mathew

Kamath

Kumar³

et al. 2017

Epilepsia Open

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“…12 Essential oils such as eucalyptus, camphor, and rosemary contain aromatic monoterpene 1,8-cineole. 13,14 1,8-Cineole has a mechanism of action similar to the known proconvulsant pentylenetetrazole. 11,15 1,8-Cineole in animal models was found to induce seizures at a dosage of 0.5 mL/kg.…”

Section: Discussionmentioning

confidence: 99%

Essential oil–related status epilepticus: A small case series study

et al. 2020

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Objective Essential oils are plant‐derived oils and are widely used as an over‐the‐counter remedy for common ailments. Many essential oils are found to have proconvulsant effects. Here we report a small case series of 3 adults with eseential oil‐related status epilepticus. Methods This was an observational study conducted in a tertiary care hospital in south India from January 2018 to December 2019. We collected the demographic, clinical, and imaging features of all cases of status epilepticus resulting from exposure to essential oils. Cases of status epilepticus secondary to all other causes were excluded. Results There were 3 young adults with essential oil‐related status epilepticus. Two had de novo generalized tonic–clonic status epilepticus, and 1 with posttraumatic occipital lobe epilepsy had focal‐impaired awareness status epilepticus. The first 2 cases presented with histories of ingestion of eucalyptus oil. The third case had focal‐impaired awareness status epilepticus after topical application of various balms containing eucalyptus and camphor. Conclusions Proconvulsant essential oils of eucalyptus and camphor can cause both generalized and focal status epilepticus. Physicians dealing with patients of status epilepticus should enquire about the exposure to proconvulsant essential oils.

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“…A study of 10 cases of EO poisoning-induced epileptic seizures based on admissions at three tertiary care hospitals located in Bengaluru, India found that the patients had been exposed to EO via inhalation (eight cases), intranasal instillation (one case), and massage (one case) [14]. From some of the available case studies we note that while the maximum number of cases may be attributed to ingestion, even topical application or inhalation of EO vapors can also result in adverse reactions [6][7][14][15][16]. Intriguingly, the Queensland study also noted that 33 children were entirely asymptomatic, including four who had reportedly swallowed more than 30 mL of EO [11].…”

Section: Introductionmentioning

confidence: 99%

A Pediatric Case of Accidental Eucalyptus Oil Poisoning from New Delhi, India: Emergency Measures, Historical Context, and Implications for Practice

Sitaraman¹,

Rao²

2019

Cureus

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Eucalyptus oil (EO) and EO containing products are readily available worldwide over the counter as topical nasal decongestants, rubefacients, anti-pyretics, and anti-inflammatory agents. However, EO is poisonous when orally ingested, or otherwise internally administered, resulting in serious outcomes such as seizures, vomiting, drowsiness, and even death. In this case report, we describe emergency measures adopted in a suspected case of EO ingestion by a 17-month-old female infant. It was found that stomach washes with normal saline followed by the oral administration of ranitidine to prevent vomiting restored and maintained normalcy over a 24-hour period. We situate our experience within the Indian context and recommend that pediatricians and healthcare workers routinely and explicitly warn parents about the serious consequences of the incorrect usage of substances containing essential oils in general and EO in particular.

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Eucalyptus oil poisoning

Cited by 21 publications

References 4 publications

Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

Eucalyptus oil inhalation–induced seizure: A novel, underrecognized, preventable cause of acute symptomatic seizure

Essential oil–related status epilepticus: A small case series study

A Pediatric Case of Accidental Eucalyptus Oil Poisoning from New Delhi, India: Emergency Measures, Historical Context, and Implications for Practice

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