Abstract:Objective Eucalyptus oil (EO)-induced seizures (EOIS) in children is a less recognized entity and a rare cause of acute symptomatic seizures. The purpose of this review outlines the clinical features and outcomes of EOIS with observed cases.
Patients and Methods We identified three pediatric patients with EOIS who were treated at Prathima Institute of Medical Sciences, Karim Nagar, India.
Results Seizures were developed in three children within 15 to 25 minutes after the ingestion of EO. All the children have … Show more
“…The higher good knowledge in health personnel 8.8% compared to parents 0.3% can be accounted for by the number of years of studies and years in practice of health personnel. This goes in line with two studies conducted in India and published in 2021 by Chandar Dudipala et al which revealed that despite the previous case reports in the literature quoting the seizurogenic potential of EO, this awareness was lacking in both clinicians and parents and that the knowledge about EO induced-seizures was essential to be disseminated among health care professionals and the general population [3,10]. 94.0% parents strongly agreed on the fact that self-medication by parents on children could bring about negative effects like convulsions.…”
Section: Discussionsupporting
confidence: 83%
“…of the Myrtaceae family and is rich in 1,8-cineole (eucalyptol) [2]. It is an expectorant used in pharmaceutical products against cough, common cold and bronchitis [1,3]. Camphorated oil and Eucalyptus essential oil (EO) can cause poisonings [3][4][5].…”
Section: Introductionmentioning
confidence: 99%
“…It is an expectorant used in pharmaceutical products against cough, common cold and bronchitis [1,3]. Camphorated oil and Eucalyptus essential oil (EO) can cause poisonings [3][4][5]. Camphorated oil is a CNS stimulant, causing mild excitation, grand mal seizures or status epilepticus in toddlers as young as 4 months [6] and even up to children aged 4-5 years [4].…”
Background: Camphor and eucalyptus essential oils contain camphor and eucalyptol respectively which serve as active ingredients in over-the-counter drugs to manage upper respiratory tract infections and pain in children. However, because of their pro-convulsant properties, seizures constitute a documented complication of their toxicity after ingestion, inhalation, and dermal exposure.
Objectives: This study aimed to assess the knowledge, attitudes and practices of parents and health personnel on the risk of onset of seizures in children exposed to pharmaceutical products containing camphor and/or eucalyptus essential oils.
Methods: This was a hospital-based cross-sectional study conducted in the Mother and Child Centre of Chantal Biya Foundation, a reference hospital. The survey was conducted using questionnaires directed to health personnel and parents of hospitalized children under 8 years old.
Results: A total of 350 parents out of the 360 encountered were included in the study and 57 health personnel out of the 100 encountered. Parents 337 (96.3%) and health personnel 18 (31.6%) had poor knowledge on the issue. Parents 338 (96.6%) and health personnel 54 (94.75%) had very satisfactory attitude scores. Both parents 319 (91.1%) and health personnel 31 (54.4%) had harmful practices scores.
Conclusion: This study showed that both parents and health personnel had poor knowledge, very satisfactory attitudes and harmful practices towards the risk of onset of seizures in children exposed to pharmaceutical products containing camphor and/or eucalyptus essential oils.
“…The higher good knowledge in health personnel 8.8% compared to parents 0.3% can be accounted for by the number of years of studies and years in practice of health personnel. This goes in line with two studies conducted in India and published in 2021 by Chandar Dudipala et al which revealed that despite the previous case reports in the literature quoting the seizurogenic potential of EO, this awareness was lacking in both clinicians and parents and that the knowledge about EO induced-seizures was essential to be disseminated among health care professionals and the general population [3,10]. 94.0% parents strongly agreed on the fact that self-medication by parents on children could bring about negative effects like convulsions.…”
Section: Discussionsupporting
confidence: 83%
“…of the Myrtaceae family and is rich in 1,8-cineole (eucalyptol) [2]. It is an expectorant used in pharmaceutical products against cough, common cold and bronchitis [1,3]. Camphorated oil and Eucalyptus essential oil (EO) can cause poisonings [3][4][5].…”
Section: Introductionmentioning
confidence: 99%
“…It is an expectorant used in pharmaceutical products against cough, common cold and bronchitis [1,3]. Camphorated oil and Eucalyptus essential oil (EO) can cause poisonings [3][4][5]. Camphorated oil is a CNS stimulant, causing mild excitation, grand mal seizures or status epilepticus in toddlers as young as 4 months [6] and even up to children aged 4-5 years [4].…”
Background: Camphor and eucalyptus essential oils contain camphor and eucalyptol respectively which serve as active ingredients in over-the-counter drugs to manage upper respiratory tract infections and pain in children. However, because of their pro-convulsant properties, seizures constitute a documented complication of their toxicity after ingestion, inhalation, and dermal exposure.
Objectives: This study aimed to assess the knowledge, attitudes and practices of parents and health personnel on the risk of onset of seizures in children exposed to pharmaceutical products containing camphor and/or eucalyptus essential oils.
Methods: This was a hospital-based cross-sectional study conducted in the Mother and Child Centre of Chantal Biya Foundation, a reference hospital. The survey was conducted using questionnaires directed to health personnel and parents of hospitalized children under 8 years old.
Results: A total of 350 parents out of the 360 encountered were included in the study and 57 health personnel out of the 100 encountered. Parents 337 (96.3%) and health personnel 18 (31.6%) had poor knowledge on the issue. Parents 338 (96.6%) and health personnel 54 (94.75%) had very satisfactory attitude scores. Both parents 319 (91.1%) and health personnel 31 (54.4%) had harmful practices scores.
Conclusion: This study showed that both parents and health personnel had poor knowledge, very satisfactory attitudes and harmful practices towards the risk of onset of seizures in children exposed to pharmaceutical products containing camphor and/or eucalyptus essential oils.
“…Of the remaining 32 articles, 15 satisfied all the inclusion criteria for our review. 5–19 Out of these, three were prospective observational studies, three retro-spective studies or case record reviews, six small case series and three single case reports. Figure 1.Flow diagram of the study selection process.…”
Seizures triggered by skin application, inhalation or ingestion of over-the-counter medications containing eucalyptus oil are known. We report five children who suffered likewise. We made a systematic search for all reported cases and performed a pooled analysis to provide a comprehensive estimate of the type of seizures, their management and outcome. In 110 cases (49 children), inhalational use was the most predominant, generalised tonic-clonic (the commonest semiology) and levetiracetam was the most common anti-convulsant treatment used. Most cases had an uneventful recovery. Adults were less likely to have prolonged and multiple seizures, requiring intensive care or mechanical ventilation.
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