Etude quantitative et thermodynamique des phénotypes érythrocytaires « A faible

Weak A Phenotypes Possibly Caused by Mutation

“…The H transferase activities in their serums were within the normal range. (4) Absence of the A transferase activity in the sera of members of the L. family with postulated Ay phenotypes is in agreement with earlier data of Cartron et al [8], Subsequently, however, employing prolonged incubation times, Cartron [9] reported very weak A transferase activ ities ranging from '/so to V200 of control samples in 4 unrelated Ai individuals. Initially, we have also reported very weak A transferase activities in the sera of the mem bers of the L. family with weak A phenotypes [10].…”

Weak A Phenotypes Possibly Caused by Mutation1

“…Subsequently, however, employing prolonged incubation times, Curtron [9] reported very weak A transferase activities ranging from 1/50 to 1 / 2 w of control samples in 4 unrelated Al individuals. Initially, we have also reported very weak A transferase activities in the sera of the members of the L. family with weak A phenotypes [ 101.…”

“…The H antigen was well expressed (see table 11). Scores estimated according to Curtron [9]. The brothers were secretors, but the amounts of A antigen in their salivas were extremely small (see table 111).…”

ABO, H, and Lewis Systems

“…In India there is more variation with a high frequency of Se in the North (up to 0.75) and low frequency in the South (0.22). Measurements of relative agglutinability, obtained by counting the number of cells agglutinated by anti -A in a cell counter, and site density, determined with radiolabelled rabbit IgG anti -A [223,224] , are shown in Table 2.15 . In many cases weak A subgroups have been found and associated with ABO mutations although serological analyses have been insuffi cient for categorising the phenotype, usually because of unavailability of secreted material.…”