Etude De Relation Des Groupes Sanguins (Abo) Et Rhésus (Standard) Dans Le Diabète

Zeytinoglu, I

doi:10.1159/000150899

Cited by 2 publications

(1 citation statement)

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“…Berg et al (1967) found a significant excess of the cDE (R2) haplotype among their diabetics while Scholz et al (1975) found that the CDe (R1) and cde (r) haplotypes were increased in frequency among diabetics, though the differences were not significant. None of the series which reported results for the D locus only (Craig and Wang, 1955;McConnell et al, 1956;Zeytinoglu, 1956;Anderson and Lauritzen, 1960;Simpson et al, 1962) found significant differences between diseased and non-diseased groups.…”

Section: The Abo Systemmentioning

confidence: 99%

Genetic polymorphisms in diabetics and non-diabetics.

Williams¹,

Cartwrigth²

1979

Journal of Medical Genetics

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Section: The Abo Systemmentioning

confidence: 99%

Genetic polymorphisms in diabetics and non-diabetics.

Williams¹,

Cartwrigth²

1979

Journal of Medical Genetics

View full text Add to dashboard Cite

Association of ABO blood groups with type-2 diabetes mellitus and its complications

Biplab¹,

Shukla²,

Ak³

et al. 2018

jdmdc

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Background: As type 2 DM has posed challenging and formidable problem globally lots of scientific research work have been targeted and concepts are evolving every other day to unleash newer etiological factor in its causation and side by side risk factors so that proper aggressive strategy can be instituted to contain the disease at the very outset. Keeping these ideas in the back of our mind we embarked upon this small but compact path finding study. Methodology:The study conducted in the Dept. of Endocrinology, Medical College and Hospital, Kolkata. Patients suffering from Type-2 DM (diagnosed by ADA criterion) attending our diabetic clinic and diabetic patients admitted including the Dept. of Endocrinology and Internal Medicine were selected for this study. Study was conducted from March 2013 to December 2014. 276, Type-2 diabetic patients and 117 healthy control subjects among the relative of patients and volunteers were selected for this study to compare distribution of ABO blood groups. All the study subjects were selected by random sampling technique. ABO blood grouping (determined by using Tulip Diagnostic Kit). Screening of complications done by appropriate clinical examinations and laboratory investigations.Results: Total 276 patients with type 2 DM were included in this study. Of those 276 diabetic patients 152(55%) were male and 124(45%) were female. 117 healthy control subjects among the relative of patients and volunteers were selected for this study to compare distribution of ABO blood groups. Mean age of diabetic patient was 50.46(±10.38) and non-diabetic control subjects was 40.52(±12.21). Mean BMI was 24.18(±3.77) in diabetic subjects and was 25.40(±3.92) in control population. Chi-square statistical analysis among different blood groups between non-diabetic (n=111) and diabetic population (N=276) revealed no significant relationship of any blood group with type 2 DM (p˃0.05). But relative risk (RR) were calculated in reference to blood group O, it has been observed that slight increase of risk of developing type 2 DM among AB( RR 1.075), A(1.044) and B(1.033).With regards to distribution of patients (in number) with type 2 DM with different microvascular complications, Nephropathy was the most common complication observed among different blood groups (37.2% in B, 36.6% in O, 36.5% in A and 34.5% in AB).Further exploring the association between specific blood groups in type 2 diabetes subjects and microvascular complications, no significant association observed with type 2 DM and neuropathy, nephropathy and retinopathy (p˃0.05). However, taking blood group O as a reference group, Blood group AB (RR 0.583 and blood group A(RR0.698) were less likely to develop neuropathy compare to blood group O. However no difference in relative risk found for development of nephropathy and retinopathy. Conclusion:We found that person with O+ve blood group has least chance of developing Type 2 DM whereas subject with AB+ve blood group are more vulnerable to develop Type 2 DM. Therefore, the effects of blood group...

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Etude De Relation Des Groupes Sanguins (Abo) Et Rhésus (Standard) Dans Le Diabète

Cited by 2 publications

References 0 publications

Genetic polymorphisms in diabetics and non-diabetics.

Genetic polymorphisms in diabetics and non-diabetics.

Association of ABO blood groups with type-2 diabetes mellitus and its complications

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