Étude de 22 observations de neuroBehçet dans une série de 170 maladies de Behçet

Neuro-Behçet, pseudotumor cerebri and ocular signs: a rare association

“…The most appropriate medical treatment consists of corticosteroids associated with immunosuppression, in different combinations [ 7 ], [ 13 ], [ 35 ], [ 37 ], [ 42 ], [ 43 ]. The immunosuppression was initially achieved by cyclosporine, but because of the severity of the symptoms in this case and the eventual neurotoxicity of the drug [ 36 ], [ 38 ], [ 44 ], [ 45 ], it was replaced by cyclophosphamide [ 5 ], [ 6 ], [ 12 ], [ 46 ].…”

“…Treatment aims to suppress the inflammation and must be administered as early as possible [ 35 ]. Therefore, the frequency and intensity of relapses may be minimized, avoiding further eye injuries.…”

“…Therefore, the frequency and intensity of relapses may be minimized, avoiding further eye injuries. Despite treatment, the natural progression of the disease is by attacks and remissions [ 35 ].…”

Imaging Features of Behçet’s Disease

“…The linear hyperintense T2 lesions of the posterior arm of the internal capsule are very evocative of NBD (Tali et al 1997). Patients with a more diffuse meningoencephalitis show hyperintense T2 lesions within the subcortical white matter of the temporal, Tohmé et al 2009). An associated meningeal thickening with contrast enhancement has been also reported (Guma et al 1998;Akman-Demir et al 1999;Kidd et al 1999;Chae et al 2008).…”

“…CT and routine MRI may not be contributory. However, DWI and ADC values can be very helpful and stereotaxic biopsy may be necessary to establish the diagnosis (Matsuo et al 2005;Darmoul et al 2006;Chae et al 2008;Tohmé et al 2009). …”