Etretinate in the Treatment of Ulcerative Lichen planus

Joshi, Rajendra K.; Abanmi, Abdullah; Jouhargy, E.; Horaib, A.

doi:10.1159/000247204

Cited by 10 publications

(10 citation statements)

References 6 publications

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“…Our patient was given systemic etretinate on the basis of the good response reported by Joshi et al 2 We found a satisfactory response in our patient, and propose this as an alternative therapy to skin grafting when surgery is refused.…”

Section: Discussionsupporting

confidence: 66%

“…Ulcerative lichen planus (ULP) of the sole is an unusual variant of LP, described as a separate entity for the first time by Cram et al 1 in 1966, and less than 50 patients have been reported in the literature 2 …”

Section: Discussionmentioning

confidence: 99%

“…In recent years, other medical treatments have been suggested, e.g. dapsone, 6 etretinate, 2 and cyclosporine A 7 have been found to be effective in some cases; in other cases, no improvement was observed 8 …”

Section: Discussionmentioning

confidence: 99%

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Ulcerative lichen planus of the sole with rheumatoid arthritis

1998

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Section: Discussionsupporting

confidence: 66%

Section: Discussionmentioning

confidence: 99%

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Ulcerative lichen planus of the sole with rheumatoid arthritis

1998

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“…Few cases have been reported in the literature since the first description by Friedman in 1921 5. It is an adult-onset disease and women are more affected than men 6. It is scharacterized by chronic, painful, disabling, large and superficial ulcers which show irregular form, inflammation, and an exsudative base.…”

Section: Discussionmentioning

confidence: 99%

Erosive lichen planus of the soles: Effective response to prednisone

et al. 2011

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BackgroundErosive lichen planus (LP) of the soles is a rare variant of LP, characterized by chronic, painful, and disabling plantar ulcerations. Herein, we report a case with complete healing following treatment with systemic steroids.Case reportA 38-year-old woman was referred with painful and disabling erosive bilateral plantar LP, which she had experienced for 6 weeks. A 1 mg/kg/day, oral prednisone therapy led to rapid improvement and complete healing within 3 weeks, with a sustained result under a low dose maintenance therapy.DiscussionUlcerative plantar LP is significantly known to be unresponsive to several topical and systemic therapies. Surgical excision and grafting is the treatment of choice. Systemic steroids are reported to have inefficient or partial results; both on cutaneous healing and on maintenance of the result. Our patient achieved complete cicatrisation with a sustained result of 3 months under a low dose of prednisone (5 mg/day).

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“…Ulcerative lichen planus of the sole is an unusual variant of lichen planus, with only a few reported cases in the literature (2).…”

Section: Introductionmentioning

confidence: 99%

Therapeutic Hotline: Ulcerative lichen planus - treatment challenges

Sălăvăstru

Tiplica

2010

Dermatologic Therapy

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Ulcerative lichen planus of the sole is an unusual variant of lichen planus, with only a few reported cases in the literature. The present authors present the case of a 77-year-old woman with relapsing erosive lichen planus of the feet with large, ill-defined and painful ulcers of the soles, which were present for 24 months and made her walking almost impossible. Ulcerative lichen planus is remarkably known as unresponsive to usual local and systemic therapies, and the cutaneous plantar lesions are even more difficult to treat. In our patient, we achieved very good results with topically applied tacrolimus ointment 0.1%, twice a day. The pain disappeared at the end of the first week of treatment, and after 4 weeks, the ulcerations were 95% epithelized, and the patient was able to walk without any discomfort. During the treatment, the present authors did not notice any undesirable secondary effects.

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Etretinate in the Treatment of Ulcerative Lichen planus

Cited by 10 publications

References 6 publications

Ulcerative lichen planus of the sole with rheumatoid arthritis

Ulcerative lichen planus of the sole with rheumatoid arthritis

Erosive lichen planus of the soles: Effective response to prednisone

Therapeutic Hotline: Ulcerative lichen planus - treatment challenges

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