Atopic Dermatitis - Eczema 2023
DOI: 10.1007/978-3-031-12499-0_5
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Etiopathophysiology of Atopic Eczema

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“…Furthermore, the pandemic’s everyday life was characterized by isolation and anxiety about the well-being of loved ones, as reported by Lewicka et al, which has been associated with increased stress and anxiety levels [ 33 ]. The existing literature indicates that specific stressors have been linked to more frequent exacerbations and a deteriorating course of disease in patients with atopic dermatitis [ 34 , 35 ]. Stress is a well-established trigger for atopic dermatitis and can disrupt the proper functioning of the skin’s epidermal barrier through mechanisms involving the stress-induced secretion of endogenous glucocorticoids, potentially leading to damage to the skin barrier [ 36 , 37 ].…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, the pandemic’s everyday life was characterized by isolation and anxiety about the well-being of loved ones, as reported by Lewicka et al, which has been associated with increased stress and anxiety levels [ 33 ]. The existing literature indicates that specific stressors have been linked to more frequent exacerbations and a deteriorating course of disease in patients with atopic dermatitis [ 34 , 35 ]. Stress is a well-established trigger for atopic dermatitis and can disrupt the proper functioning of the skin’s epidermal barrier through mechanisms involving the stress-induced secretion of endogenous glucocorticoids, potentially leading to damage to the skin barrier [ 36 , 37 ].…”
Section: Discussionmentioning
confidence: 99%