Étiopathogénie des modifications de la pression intraoculaire au cours des uvéites

Souissi, K.; Afrit, M.A. El; Trojet, S.; Kraiem, A.

doi:10.1016/s0181-5512(06)77711-7

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…The subendothelial region also showed an increase in plaques and fibrillar material. In addition, secondary iridocorneal angle closure may occur in uveitis by various mechanisms: posterior synechiae with pupillary block, peripheral anterior synechiae, forward rotation of the ciliary body [73]. Nearly 11% of patients develop peripheral anterior synechiae (PAS) secondary to inflammation [70].…”

Section: Uveitic Glaucomamentioning

confidence: 99%

The trabecular meshwork: Structure, function and clinical implications. A review of the literature

Buffault

Labbé

Hamard

et al. 2020

Journal Français d'Ophtalmologie

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Glaucoma is a blinding optic neuropathy, the main risk factor for which is increased intraocular pressure (IOP). The trabecular meshwork, located within the iridocorneal angle, is the main pathway for drainage of aqueous humor (AH) out of the eye, and its dysfunction is responsible for the IOP elevation. The trabecular meshwork is a complex, fenestrated, threedimensional structure composed of trabecular meshwork cells (TMC) interdigitated into a multilayered organization within the extracellular matrix (ECM). The purpose of this literature review is to provide an overview of current understanding of the trabecular meshwork and its pathophysiology in glaucoma. Thus, we will present the main anatomical and cellular bases for the regulation of aqueous humor outflow resistance, the pathophysiological mechanisms involved in trabecular dysfunction in the various types of glaucoma, as well as current and future therapeutic strategies targeting the trabecular meshwork.

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Section: Uveitic Glaucomamentioning

confidence: 99%