Etiopathogenesis of sacroiliitis: implications for assessment and management

Baronio, Manuela; Sadia, Hajra; Paolacci, Stefano; Prestamburgo, Domenico; Miotti, Danilo; Guardamagna, Vittorio; Natalini, Giuseppe; Bertelli, Matteo

doi:10.3344/kjp.2020.33.4.294

Cited by 10 publications

(14 citation statements)

References 90 publications

(99 reference statements)

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“…3 This study aimed to highlight an important but possibly overlooked cause of inflammatory back pain due to active sacroiliitis in gout patients. 4 Inflammatory low back pain, as seen in the spondyloarthritides, usually has an insidious onset and is more common in patients younger than 40 years.…”

Section: Discussionmentioning

confidence: 99%

“…A retrospective analysis of our hospital records showed that other crystals associated with arthritis, such as pyrophosphates, can be deposited in the lumbar spine, with approximately 11 cases reported in the literature 3 . This study aimed to highlight an important but possibly overlooked cause of inflammatory back pain due to active sacroiliitis in gout patients 4 . Inflammatory low back pain, as seen in the spondyloarthritides, usually has an insidious onset and is more common in patients younger than 40 years.…”

Section: Discussionmentioning

confidence: 99%

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Gouty sacroiliitis: A case report of an often‐overlooked cause of inflammatory back pain

Guo

Zheng

et al. 2022

Int J of Rheum Dis

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Gout is a chronic disease caused by monosodium urate crystal deposition, typically affecting the big toe, midfoot, and ankle. As it rarely involves the sacroiliac joints, it could be easily misdiagnosed as spondylarthritis. Here, we report the case of a patient with a long history of gout with recurrent low back pain. Computed tomography of the sacroiliac joint suggested sacroiliac arthritis, puncture biopsy indicated gout granuloma, and polarized light microscopy confirmed monosodium urate crystal deposits.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Gouty sacroiliitis: A case report of an often‐overlooked cause of inflammatory back pain

Guo

Zheng

et al. 2022

Int J of Rheum Dis

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“…Sacroiliitis is a hallmark of seronegative spondyloarthropathies. However, it also may be associated with inflammatory bowel diseases or infections such as brucellosis and tuberculosis [20]. In addition, positive sacroiliac screening tests may account for as many as 20% of asymptomatic persons in the general population [21].…”

Section: Discussionmentioning

confidence: 99%

“…It has been suggested that isotretinoin causes some changes in the lysosomal membrane structure of cells, making synovial cells prone to degenerative processes and more susceptible to mild trauma. Reports of sacroiliitis in AV athletes treated with isotretinoin may be in favour of this hypothesis [8]; however, microtrauma can cause sacroiliitis itself [20].…”

Section: Discussionmentioning

confidence: 99%

Oral isotretinoin and sacroiliitis: causal link or coincidence? Discussion points emerging from a case-based review

Sargın¹,

Manzo

2022

Reumatologia

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Isotretinoin is a retinoid derivative drug used in acne vulgaris treatment. Sacroiliitis has been reported as an uncommon adverse effect following isotretinoin treatment. We report a 30-yearold male patient who developed sacroiliitis after isotretinoin use. Stopping treatment with isotretinoin resulted in a complete disappearance of inflammatory back pain. A literature search was performed to assess the relevance of this association in everyday clinical practice, and to discuss whether the link between isotretinoin and sacroiliitis is causal or coincidental.

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“…Ankylosing spondylitis (AS) is a chronic inflammatory disease and a common type of autoimmune spondyloarthropathy that generally impacts joints of the spine, leading to chronic and severe pain; moreover, it is possible to lead to spine fusion in advanced subjects 6 . In more complex spondyloarthropathy cases, the first presentation is usually sacroiliitis, such as rheumatic disease, psoriasis, inflammatory bowel disease, Crohn's disease, and AS 7 . In this study, we present a case of FMF with the uncommon presentation of AS, a rare manifestation of FMF.…”

Section: Introductionmentioning

confidence: 99%

A case of familial Mediterranean fever presenting with ankylosing spondylitis: A rare case‐report

Khalaji,

Jafarpour

2023

Clinical Case Reports

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Key Clinical MessageThe association of familial Mediterranean fever and ankylosing spondylitis is rare, but it is essential to consider this diagnosis in patients with a history of FMF who develop symptoms of back pain or other rheumatologic conditions.AbstractFamilial Mediterranean fever (FMF) is an inherited inflammatory disorder characterized by recurrent fever episodes, abdominal pain, and arthralgia. Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects the spine's joints. The association of FMF and AS is rare. We report the case of a 22‐year‐old male patient with a history of FMF and a positive family history of FMF in his father, who presented with inflammatory back pain. The patient was found to have sacroiliitis on MRI, which is a characteristic feature of AS. The patient was negative for HLA‐B27, a genetic marker often associated with AS. This case report highlights the importance of considering AS in patients with a history of FMF who develop back pain symptoms or other rheumatologic conditions.

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Etiopathogenesis of sacroiliitis: implications for assessment and management

Cited by 10 publications

References 90 publications

Gouty sacroiliitis: A case report of an often‐overlooked cause of inflammatory back pain

Gouty sacroiliitis: A case report of an often‐overlooked cause of inflammatory back pain

Oral isotretinoin and sacroiliitis: causal link or coincidence? Discussion points emerging from a case-based review

A case of familial Mediterranean fever presenting with ankylosing spondylitis: A rare case‐report

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