1999
DOI: 10.1097/00006454-199902000-00004
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Etiology and treatment of community-acquired pneumonia in ambulatory children

Abstract: Although a possible microbial etiology was identified in 43% of the evaluable patients, clinical findings and results of blood cultures, chest radiographs and white blood cell and differential counts did not distinguish patients with a defined etiology from those without a known cause for pneumonia. There were no differences in the clinical responses of patients to the antimicrobial regimens studied.

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Cited by 283 publications
(203 citation statements)
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References 26 publications
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“…Acute M. pneumoniae and/or C. pneumoniae infection was diagnosed if the patient showed a significant antibody response to one of the pathogens in paired sera (M. pneumoniae: specific IgM $1:100, specific IgG $1:400, or a four-fold increase in IgG titre; C. pneumoniae: specific IgM $1:16, specific IgG $1:512, or a four-fold increase in IgG titre) and/or if the PCR on nasopharyngeal aspirates was positive for DNA from one of the two organisms [20].…”
Section: Methodsmentioning
confidence: 99%
“…Acute M. pneumoniae and/or C. pneumoniae infection was diagnosed if the patient showed a significant antibody response to one of the pathogens in paired sera (M. pneumoniae: specific IgM $1:100, specific IgG $1:400, or a four-fold increase in IgG titre; C. pneumoniae: specific IgM $1:16, specific IgG $1:512, or a four-fold increase in IgG titre) and/or if the PCR on nasopharyngeal aspirates was positive for DNA from one of the two organisms [20].…”
Section: Methodsmentioning
confidence: 99%
“…Wubbel et al 83 (Tabela 1) fizeram uma análise etioló-gica utilizando-se de cultura, PCR e sorologia em 168 crianças na faixa etária dos 6 meses a 16 anos, portadoras de PAC, e atendidas em um centro de emergências no Texas, no período de 1996 a 1997. O agente etiológico foi identificado em 43% dos pacientes, sendo o Streptococcus pneumoniae identificado em 27% dos casos, seguido pelo Mycoplasma pneumoniae em 7%, e Chlamydia pneumoniae em 6%.…”
Section: Etiologia Das Pneumonias Agudas Adquiridas Na Comunidade (Paunclassified
“…Os estudos realizados na Europa e na América do Norte demonstraram que esses agentes podem ser responsáveis por até um terço das pneumonias adquiridas na comunidade em crianças 83,84,87,112 . Faltam estudos que esclareçam o papel desses agentes em PAC, nos países em desenvolvimento 113 .…”
Section: Conclusõesunclassified
“…Among bacteria, Streptococcus pneumoniae continues to be the most significant pathogen in children of all ages (9). Group A streptococcal pneumonia is much less common.…”
Section: Etiologymentioning
confidence: 99%