Etiology and Management of Chronic Gastritis

The incidence of anastomotic leakage after esophagectomy for cancer and reconstruction with the stomach was analyzed with respect to the presence of coexistent atrophic chronic gastritis (ACG). Of a total of 28 operated esophageal cancer patients with ACG, 6 patients developed an anastomotic leak at the cervical esophagogastrostomy (21%). Of a total of 8 operated esophageal cancer patients none of the patients developed an anastomotic leak. The ACG positive and the ACG negative patients were found to be well matched for age, sex, type of operation, transplant route, level of the anastomoses, and suture technique, and all were operated on by the same surgeons. The difference in leakage rate did not reach statistical significance.

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“…Both ACG and SCCE are age related [4] and are linked to tobacco smoking and alcohol consumption [5,6). This may account for our findings as well.…”

Section: Discussionsupporting

confidence: 68%

“…One of the main reasons for the high incidence of ACG in SCCE patients may be the presence of some epidemiological and/or etiological similarities between the two conditions. Both ACG and SCCE are age related [4] and are linked to tobacco smoking and alcohol consumption [5,6). This may account for our findings as well.…”

Section: Discussionmentioning

confidence: 99%

Atrophic chronic gastritis and esophagogastric anastomotic leak after resection and reconstruction for esophageal carcinoma

Rakic

Peško

Milićević

et al. 1992

Journal of Surgical Oncology

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Exploring the mechanism of Radix pseudostellariae in the treatment of chronic gastritis based on network pharmacology and molecular docking techniques

Li,

Chen,

Zhai

et al. 2024

Preprint

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Radix pseudostellariae (RP) has been used for the treatment of various diseases, including gastric disorders such as Chronic gastritis (CG), However, the multi-targeting mechanism of RP on CG still needs to be clarified. Drug targets were established through TCMSP, PubChem and Swiss Target Prediction online database. GeneCards database was used to search for chronic gastritis related targets. Cytoscape was utilized to construct the "drug-active ingredient-target" network relationship diagram. Venny plots of drug targets and disease targets were obtained from online software to get the intersecting genes, and the coincidence targets were imported into STRING database to construct a PPI network. The intersecting targets were subjected to pathway enrichment analysis KEGG and GO functional enrichment analysis with the help of the DAVID database. Molecular docking was performed by Autodocktools software and then visualized by PYMOL. 8 active ingredients and 117 action targets were obtained for Radix Pseudostellariae, 758 action targets for chronic gastritis disease, 31 intersecting targets for Radix Pseudostellariae in chronic gastritis were obtained. PPI network analysis showed that the core targets of the drug affecting chronic gastritis were TNF, MMP9, AKT1, etc. The molecular docking validation results showed good binding of core components and core targets.

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A Case Report of the Traditional Korean Treatment of Female Patients with Both Functional Dyspepsia and Chronic Atrophic Gastritis

Yoon¹

2019

J Int Korean Med

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Etiology and Management of Chronic Gastritis

Cited by 3 publications

References 19 publications

Atrophic chronic gastritis and esophagogastric anastomotic leak after resection and reconstruction for esophageal carcinoma

Atrophic chronic gastritis and esophagogastric anastomotic leak after resection and reconstruction for esophageal carcinoma

Exploring the mechanism of Radix pseudostellariae in the treatment of chronic gastritis based on network pharmacology and molecular docking techniques

A Case Report of the Traditional Korean Treatment of Female Patients with Both Functional Dyspepsia and Chronic Atrophic Gastritis

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