Ethylene Glycol Induced Hyperoxaluria Increases Circulating Endothelial Cells in Peripheral Blood: A Possible Link of Urolithiasis to Cardiovascular Diseases
Abstract:The aim of this study was to establish the role of hyperoxaluria on endothelial dysfunction by using Circulating Endothelial Cells (CECs). A total of 24 Sprague Dowley rats have been included into study. Group IA, B and C (n=6 in each): Hyperoxaluria-induced group; Group II (n=6): Control group. Rats were euthanized after collection of 24-hour urine samples for the analysis of oxalate excretion either at 24 th hour (group A), 14 th day (group B) or 28 th day (group C) and blood samples were collected for the a… Show more
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