Ethnomedical survey of Berta ethnic group Assosa Zone, Benishangul-Gumuz regional state, mid-west Ethiopia

Flatie, Teferi; Fenta, Teferi Gedif; Asres, Kaleab; Gebre‐Mariam, Tsige

doi:10.1186/1746-4269-5-14

Cited by 148 publications

(110 citation statements)

References 15 publications

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“…Like the present study, the local community elsewhere in Ethiopia collects medicinal plants both from the wild and semi-wild environments 13 24 and Mesfin et al 27 in the humid areas, and Adefa 1 , Zenebe et al 35 , Yirga 33,34 in semi-arid areas of Ethiopia also documented an appreciable number of medicinal plants.…”

Section: Floristic Composition Diversity and Distribution Of Medicinsupporting

confidence: 50%

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Ethnobotanical Study of Medicinal Plants in Chilga District, Northwestern Ethiopia

Tebkew¹,

Asfaw²,

Zewudie³

2015

JNR

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Ipomoea reniformis Chaos is claimed in Indian traditional medical practice to be useful in the treatment of epilepsy and neurological disorders. In the present study, pretreatment effect of methanolic extract of Ipomoea reniformis on epilepsy and psychosis was evaluated in rodents using standard procedures. Besides evaluating epileptic and behavioral parameters, neurotransmitters such as Gamma-Amino Butyric Acid (GABA) in epilepsy and in psychosis dopamine, noradrenaline and serotonin contents in the rodent brain were estimated. The extract pretreatment reduced maximal electro shock; Isoniazid (INH) and Pentylenetetrazole (PTZ) induced seizures and also significantly inhibited the attenuation of brain GABA levels by INH and PTZ in mice. These results suggested that the observed beneficial effect in epilepsy may be by enhancing the GABAergic system. The test drug also inhibited the apomorphine induced climbing and stereotyped behavior and showed significantly reduced levels of brain dopamine, noradrenaline and serotonin which may be due to blocking of central dopaminergic, noradrenergic and serotonergic pathways or by enhancing the GABAergic system. The results obtained in present study suggest that the title plant possesses antiepileptic and antipsychotic activities in rodents.

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Section: Floristic Composition Diversity and Distribution Of Medicinsupporting

confidence: 50%

“…Flatie et al 13 and Lulekal et al 24 also found roots take the highest proportion due to the efficacy of roots in treating the ailments. Conversely, leaves were the most widely used parts of plants 1,2,28,32,35 .…”

Section: Utilization and Socioeconomic Implicationmentioning

confidence: 97%

Ethnobotanical Study of Medicinal Plants in Chilga District, Northwestern Ethiopia

Tebkew¹,

Asfaw²,

Zewudie³

2015

JNR

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“…The most frequently used plant parts are bark (79%), leaves (11%), roots (7.5%) and stalks (2.1%) ( Figure 1A). It is well recognized by conservationists that medicinal plants primarily valued for their root parts and those which are intensively harvested for their bark often tend to be the most threatened by over-exploitation (Flatie et al, 2009). This is the case with all Warburgia species, with its users targeting mainly stem bark as source of ethnomedicine.…”

Section: Vernacular Names and Traditional Usesmentioning

confidence: 99%

The genusWarburgia: A review of its traditional uses and pharmacology

Maroyi

2013

Pharmaceutical Biology

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Context: Warburgia (Canellaceae) species have a long history of ethnomedicinal uses in east, central and southern Africa. Due to the popularity of Warburgia as a source of ethnomedicines; all the species are severely over-harvested throughout their distributional ranges. Objective: This review documents fragmented information on traditional uses and pharmacological evidence of the genus Warburgia. Methods: Information on Warburgia species was collected from scientific journals, books, theses and reports via library and electronic search using Medline, Pubmed, Google Scholar, ScienceDirect and Web of Science. Results: Ethnomedicinal uses of Warburgia species have been recorded from east, central and southern Africa for 30 human and 7 animal ailments. Warburgia species are used to treat gastrointestinal disorders, cold, cough and sore throat; fever or malaria, respiratory and odontological ailments. Warburgia species are rich in drimane and colorotane sesquiterpenoides, and other compounds. The extracts of Warburgia, particularly those from stem bark and leaves, exhibited a wide range of pharmacological effects, including antibacterial, antifungal, antimycobacterial, antioxidant, anti-inflammatory, antifeedant, antiplasmodial, antileishmanial, anthelmintic, cytotoxic and molluscicidal activities. Conclusion: Pharmacological results have validated the use of this genus in traditional medicine. Further investigations are needed to explore the bioactive compounds responsible for the in vitro and in vivo pharmacological effects and their mode of action.

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“…(Sterculiaceae), is used in Burkina Faso folk medecine. Leaves, bark, roots or the whole plant are used against swelling, toothache, colic, rheumatism, ear infections, asthma, cough, diarrhea, dysentery, conjunctivitis, wounds, abscess (Flatie et al, 2009;Adjanohoun et al, 1989;Ruffo, 1991;Zerbo et al, 2007, Zongo, 2013. Miyashiro et al (1994) showed that aqueous and methanolic extracts of Waltheria indica L. had a significant inhibition of HIV-1 protease.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant, analgesic and anti-inflammatory activities of the leafy stems of Waltheria indica L. (Sterculiaceae)

Yougbare-Ziebrou¹,

Lompo²,

Ouédraogo³

et al. 2016

J App Pharm Sci

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Aim of the study:The existence of numerous side effects following the use of anti inflammatory drugs has led to the present study about Waltheria indica (Sterculiaceae), prescribed in the treatment of many inflammatory diseases component to discover phytomedicines secondary effects mitigated. Materials and methods: The chemical principles have been demonstrated by test characterization in liquid medium according the method of Ciulei (1949).In vivo, the model of edema induced by carrageenan to cause inflammation and the model of acetic acid induced pain were used to assess the anti-inflammatory and analgesic activities of the extract. In vitro, the effects of the aqueous extract on the DPPH°° radical, the lipoxygenase and lipid peroxidation has been demonstrated. Results: Phytochemical study of leafy stems of the plant showed the presence of tannins, flavonoids, sterols, triterpenes, saponins, reducing compounds, coumarins etc. In vivo, the results showed the aqueous extract and anti-edematous effects of the analgesic of the plant. In vitro, the results revealed the aqueous extract of W. indica inhibited the radical of DPPH°°, the lipoxygenase and the lipid peroxidation. Conclusion:The presence of chemical compounds and biological properties obtained justify the contribution of the plant in traditional medicine for the treatment of diseases with inflammatory component.

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Ethnomedical survey of Berta ethnic group Assosa Zone, Benishangul-Gumuz regional state, mid-west Ethiopia

Cited by 148 publications

References 15 publications

Ethnobotanical Study of Medicinal Plants in Chilga District, Northwestern Ethiopia

Ethnobotanical Study of Medicinal Plants in Chilga District, Northwestern Ethiopia

The genusWarburgia: A review of its traditional uses and pharmacology

Antioxidant, analgesic and anti-inflammatory activities of the leafy stems of Waltheria indica L. (Sterculiaceae)

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