Ethnobotanical survey of presumed anti-ulcer Congolese medicinal plants

Abstract

Une enquête ethnobotanique réalisée à Brazzaville (Congo) du 10 juillet au 31 août 2004 auprès des tradithéra-peutes a permis d'inventorier vingt et une (21) plantes utilisées dans le traitement traditionnel de l'ulcère gastroduodénal. Deux de ces plantes, Ceiba pentandra, (Bombacaceae) et Helicrysum mechowianum (Asteraceae), ont été sélectionnées pour un screening chimique. Mots clés : Enquête ethnobotanique -Ceiba pentandraHelicrysum mechowianum -Profil chimique Ethnobotanical survey of presumed anti-ulcer Congolese medicinal plants Abstract: An ethnobotanical survey of traditional practitioners was carried out close to Brazzaville, Congo, from 10 July to 31 August 2004. Twenty-one plants used in the traditional treatment of gastroduodenal ulcers were inventoried. Two of them, Ceiba pentandra (Bombacaceae) and Helichrysum mechowianum (Asteraceae), were selected for chemical screening.

Protease-inhibiting, molecular modeling and antimicrobial activities of extracts and constituents from Helichrysum foetidum and Helichrysum mechowianum (compositae)

“…H. foetidum has been assessed to treat influenza, infected wounds, herpes, eye problems, menstrual pains and to induce trance and possess antifungal properties [ 2 , 26 ]. H. mechowianum is used for the treatment of stomach damage, cephalgy [ 9 , 27 ] and possesses ulcerogenic activity [ 28 , 29 ]. In continuation of these studies, w e extended our search for biologically active compounds from Helichrysum species [ 17 , 18 ] to the protease-inhibiting activity of extracts and isolated compounds from Helichrysum foetidum and Helichrysum mechowianum using a fluorescence resonance energy transfer (FRET) protease pepsin inhibition assay as pharmacological model for anti-ulcer compounds [ 30 ].…”

Ethnopharmacological survey of six medicinal plants used in the traditional treatment of urinary tract infections and other infectious diseases

“…As an example, M. indica was cited by traditional healers against several diseases in West Africa. Indeed, it is quoted against the traditional treatment of malaria in Cameroon, cardiovascular diseases in Thad, muscular contusions and Togo, and ulcers in Congo (Dongock et al, 2018;Hélé et al, 2014;Ibara et al, 2007). Beninese respondents also cited these conditions in this study.…”

Anti-Inflammatory and Analgesic Effects of Aqueous Extract of Stem Bark of <i>Ceiba pentandra</i> Gaertn

“…The phytochemical analysis of the aqueous extract of Ceiba pentandra previously performed [7] has revealed the presence of flavonoids, tannins, triterpene steroids, and quinones. The anti-inflammatory and analgesic properties of this extract observed in our study can be explained by the presence of flavonoids [9].…”

“…The incision was closed by suture. Animals were then treated with drugs for seven (7) days. On the eighth day the granulation tissue with cotton pellet was removed, cleared of adhering tissue and placed at 60˚C for 24 h and weighed.…”