Ethnobotanical survey of medicinal plants used in the Maseru district of Lesotho

Kose, L. Seleteng; Moteetee, A.; Vuuren, Sandy van

doi:10.1016/j.jep.2015.04.047

Cited by 106 publications

(61 citation statements)

References 55 publications

(31 reference statements)

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“…The rhizome or root decoction of E. elephantina is used to relieve abdominal pains in Lesotho and Zimbabwe [3, 24] and chest pains in South Africa [42] and applied to open wounds to stop bleeding [39]. In South Africa, roots and rhizomes of E. elephantina are boiled in water for external use to treat acne and other skin diseases [36–38] while roots and rhizomes of E. elephantina in combination with Pentanisia prunelloides (Klotzsch & Eckl.…”

Section: Ethnomedicinal Uses Of Elephantorrhiza Elephantinamentioning

confidence: 99%

“…In Botswana, rhizome or root powder of E. elephantina is used to wipe the anus of children with bloody diarrhoea, to clean the womb after abortion, as remedy for early menstruating children, earache, erectile dysfunction, and sexually transmitted infections [21, 40, 41]. In Lesotho, rhizome decoction of E. elephantina is used to cleanse blood, as remedy for breast cancer, herpes, infertility, intestinal disorders, stomach problems, syphilis, and tuberculosis [24, 39]. Leaf, rhizome, and root decoction of E. elephantina are used as remedy for diarrhoea and dysentery in Mozambique [45] and South Africa [15, 28, 29, 32, 38, 44, 46].…”

Section: Ethnomedicinal Uses Of Elephantorrhiza Elephantinamentioning

confidence: 99%

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Elephantorrhiza elephantina: Traditional Uses, Phytochemistry, and Pharmacology of an Important Medicinal Plant Species in Southern Africa

Maroyi

2017

Evidence-Based Complementary and Alternative Medicine

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Elephantorrhiza elephantina is used in southern Africa as traditional remedy for a wide range of human diseases and ailments including dermatological diseases, gastrointestinal system disorders, sexual dysfunction, sexually transmitted infections, and wounds. The rhizome decoction of E. elephantina is widely used by small-scale farmers in Botswana and South Africa as ethnoveterinary medicine for cattle, goats, horses, pigs, poultry, and sheep. Several classes of phytochemical compounds including anthocyanidins, anthraquinones, esters, fatty acids, phenolic compounds, flavonoids, glycosides, polysterols, saponins, sugars, tannins, and triterpenoids have been isolated from E. elephantina. Scientific studies on E. elephantina indicate that it has a wide range of biological activities including anthelmintic, antibacterial, antifungal, anti-inflammatory and antinociceptive, antiplasmodial, antioxidant, antibabesial, and antirickettsial activities. Elephantorrhiza elephantina is a valuable source of traditional medicine in southern Africa that it is worth additional research attention because of its wide ethnomedicinal applications and promising biological activities. However, the current health-related information on E. elephantina is not sufficiently explored as diverse studies on its chemical and pharmacological activities are required to understand its mechanism of action and to characterize the metabolites responsible for these activities.

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Section: Ethnomedicinal Uses Of Elephantorrhiza Elephantinamentioning

confidence: 99%

Section: Ethnomedicinal Uses Of Elephantorrhiza Elephantinamentioning

confidence: 99%

Elephantorrhiza elephantina: Traditional Uses, Phytochemistry, and Pharmacology of an Important Medicinal Plant Species in Southern Africa

Maroyi

2017

Evidence-Based Complementary and Alternative Medicine

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“…According to Victor and Keith [51] and von Staden et al [52], a species categorized as Least Concern (LC) under the IUCN Red List Categories and Criteria version 3.1 [50] can additionally be categorized either as rare, critically rare, or declining. The observed population decline of G. perpensa in Lesotho and South Africa [49, 53] is due to overexploitation as herbal medicine, destruction of its habitat, medicinal plant trade, and popularity of the species in the medicinal ( muthi ) markets. It is within this context that the current study was carried out, aimed at discussing how G. perpensa is used as a single agent or in complex herbal mixtures, and assesses the phytochemistry and pharmacology of the species.…”

Section: Introductionmentioning

confidence: 99%

From Traditional Usage to Pharmacological Evidence: Systematic Review of Gunnera perpensa L.

Maroyi

2016

Evidence-Based Complementary and Alternative Medicine

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Gunnera perpensa is the only species of the genus Gunnera that has been recorded in Africa. Its leaves, rhizomes, roots, and stems are reported to possess diverse medicinal properties and used to treat or manage various human and animal diseases and ailments. Gunnera perpensa is an ingredient in many herbal concoctions and prescriptions which have been used to induce or augment labour, postnatal medication, to treat parasitic diseases, urinary complaints, kidney problems, general body pains, sexually transmitted infections, and many other diseases. Several classes of phytochemicals including alkaloids, benzoquinones, ellagic acids, flavonoids, phenols, proanthocyanidins, tannins, and minerals have been isolated from G. perpensa. Scientific studies on G. perpensa indicate that it has a wide range of pharmacological activities including acetylcholinesterase, anthelmintic, antibacterial, antifungal, antinociceptive, anti-inflammatory, antioxidant, antitumour, lactogenic, and uterotonic. Gunnera perpensa has a lot of potential as a possible source of pharmaceutical products for the treatment of a wide range of both human and animal diseases and ailments. Some of the chemical compounds isolated from G. perpensa have demonstrated various biological activities when investigated in in vitro assays. Future research should focus on the mechanisms of action of the isolated compounds, their efficacy, toxicity, and clinical relevance.

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“…Hyraceum is also used in combination with other medicinal plant species to enhance its efficacy (Seleteng-Kose et al, 2015). The strongly aromatic hyraceum is also a well-known Khoikhoi medicine, often used as a post-natal medicine for mothers and babies and a remedy for hysteria and epilepsy (van Wyk, 2008).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Procavia capensis hyraceum used in traditional medicine for antioxidant activity

Magama¹,

Rantsâ€TMo²,

Asita³

et al. 2018

J. Med. Plants Res.

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Hyraceum (HM) used in traditional medicine in Southern Africa is produced by the herbivore Procavia capensis. It is fossilized excreta derived from urine, faecal matter and plant material. In this study, qualitative phytochemical screening, determination of in vitro antioxidant activity using 1, 1-Diphenyl-2picrylhydrazyl (DPPH) and hydrogen peroxide scavenging methods, and determination of the total phenolic content in crude methanolic (95%) extract were done. Phytochemical screening detected the major phytochemical classes in the hyraceum extract as terpenoids, saponins, polyphenols, quinones, phlobatannins and coumarins with minor components as flavonoids, alkaloids, tannins, simple phenols, anthocyanins, anthraquinones and amino acids. Total phenolics content was 37.339 mg gallic acid equivalents per gram dry weight (mgGAE/g DW). Effective concentration at 50% (EC 50 ) for HM and L-ascorbic (AA) in DPPH assay was 5.983 and 0.429 µg/ml, respectively while in H 2 O 2 scavenging assay, EC 50 was 5.059 and 1.666 µg/ml, respectively. The antioxidant activity of HM could have been due to the various phenolic and terpenoid antioxidants in the HM. The findings implied that HM was slightly stronger at scavenging H 2 O 2 than at scavenging DPPH. Bioactive compounds in HM could potentially be exploited in further studies as potential antioxidants of therapeutic value.

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Ethnobotanical survey of medicinal plants used in the Maseru district of Lesotho

Cited by 106 publications

References 55 publications

Elephantorrhiza elephantina: Traditional Uses, Phytochemistry, and Pharmacology of an Important Medicinal Plant Species in Southern Africa

Elephantorrhiza elephantina: Traditional Uses, Phytochemistry, and Pharmacology of an Important Medicinal Plant Species in Southern Africa

From Traditional Usage to Pharmacological Evidence: Systematic Review of Gunnera perpensa L.

Evaluation of Procavia capensis hyraceum used in traditional medicine for antioxidant activity

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