Ethnobotanical survey of medicinal plants used as anthelmintic remedies in Gabon

Ndob, Idensi Bajin ba; Mengome, Line Edwige; Bourobou, Henri-Paul Bourobou; Banfora, Yvon Lossangoye; Bivigou, Francis

doi:10.1016/j.jep.2016.06.026

Cited by 25 publications

(16 citation statements)

References 112 publications

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“…Another clarification of the study is that medicinal plants are mostly used as mixtures, prepared as decoctions and taken orally. This is consistent with previous studies of other pathologies (Asnake et al, 2016;Kantati et al, 2016;Ndob et al, 2016). Plant mixtures are justified by healers as either enhancing the therapeutic effect or minimizing the side effects of the main plant remedy.…”

Section: Discussionsupporting

confidence: 91%

Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

et al. 2020

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Liver disease is highly prevalent in Africa, especially in the western African country Burkina Faso, due to the presence of multiple biological and chemical aggressors of the liver. Furthermore, diagnosis and appropriate care for liver disease are uneven and usually insufficient. This drives local communities to turn to folk medicine based on medicinal plants from healers. Small scale, ethnopharmacological studies on reputed hepatoprotective plants have been carried out in defined regions worldwide, but so far, no study has been carried out on a countrywide scale. Therefore, we have explored traditional healers’ practices in all thirteen regions of Burkina Faso. We interviewed 575 healers and we compiled a database with 2,006 plant entries. Here, we report results on liver nosology, liver pathologies, medicinal plants used for liver disease, and traditional practices through the lens of Burkinabe healers. Our goal was to give a full inventory of medicinal plants used to treat liver disease and to determine if there was consensus on the use of specific plants for specific symptoms. Analysis of the medicinal plants in use across the whole country provides local communities with a wider evidence base to determine which plants may be more effective in treating liver disease and could provide the scientific community, with a shortlist of plants suitable for chemical and pharmacological investigation to validate the plants’ therapeutic role.

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Section: Discussionsupporting

confidence: 91%

Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

et al. 2020

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“…A technical resource for the prevention and treatment of different veterinary diseases is the use of medicinal plants. Plants have already been used for medical purposes by ancient civilizations and are currently considered a more sustainable and more easily accessible therapeutic and/or preventive alternative to synthetic drugs [ 7 , 8 ]. These potential advantages have favored the search for new herbal or plant-derived agents for veterinary use, particularly those for the control of gastrointestinal parasites, including H. contortus [ 9 ].…”

Section: Introductionmentioning

confidence: 99%

Essential oils of Citrus aurantifolia, Anthemis nobile and Lavandula officinalis: in vitro anthelmintic activities against Haemonchus contortus

et al. 2018

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BackgroundInfections of sheep with gastrointestinal parasites, especially Haemonchus contortus, have caused serious losses in livestock production, particularly after the emergence of resistance to conventional anthelmintics. The search for new anthelmintic agents, especially those of botanical origin, has grown substantially due to the perspective of less contamination of meat and milk, as well as other advantages related to their cost and accessibility in less developed countries. The aim of this study was to evaluate the in vitro anthelmintic activity of essential oils of the plant species Citrus aurantifolia, Anthemis nobile and Lavandula officinalis against the main developmental stages of the parasite H. contortus.ResultsPlant species were selected based on substantial ethnopharmacological information. Analysis of the composition of each oil by gas chromatography coupled to mass spectrometry (GC-MS) demonstrated the presence of limonene (56.37%), isobutyl angelate (29.26%) and linalool acetate (35.97%) as the major constituents in C. aurantifolia, A. nobile and L. officinalis, respectively. Different concentrations of each oil were tested in vitro for their capacity to inhibit egg hatching (EHT), larval development (LDT) and adult worm motility (AWMT) using a multidrug-resistant strain of H. contortus (Embrapa 2010). The IC50 values obtained for the oils of C. aurantifolia, A. nobile and L. officinalis were 0.694, 0.842 and 0.316 mg/ml in the EHT and 0.044, 0.117 and 0.280 mg/ml in the LDT, respectively. The three oils were able to inhibit adult worm motility completely within the first 8–12 h of observation in the AWMT.ConclusionsThe present results demonstrate significant anthelmintic activity of the three oils against the different developmental stages of H. contortus. Furthermore, this study is of ethnopharmacological importance by validating the anthelmintic activity of the oils studied. Although new experiments are necessary, these data contribute to the development of pharmaceutical-veterinary products for sheep farming by opening up new therapeutic possibilities against gastrointestinal infections caused by H. contortus.

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“…Besides this, the preponderance of this family accounts for its importance in traditional medicine. Fabaceae family is well-known in Africa and contributes to the treatment of several diseases such as hemorrhoids (Dibong et al, 2015), vaginitis (Ndjib et al, 2017), helminthiasis (Bajin Ba Ndob et al, 2016). The similarity between the predominant families elsewhere and those of the regions studied, testifies to the richness of these areas flora.…”

Section: Discussionmentioning

confidence: 90%

Ethnobotanical study of plants used against onchocerciasis in the far north region of Cameroon

Mamat¹,

̄la²,

Christelle³

et al. 2020

J. Med. Plants Res.

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Despite the multitude of studies which have shown the use of medicinal plants in the management of parasitic diseases, little data was available on the plants used against onchocerciasis. Ethnobotanical surveys were carried out among traditional healers in the Far North region of Cameroon. Studies were conducted from July 2017 to May 2018 through direct interviews using a semi-structured questionnaire taking into consideration the socio-demographic characteristics of the respondents as well as their knowledge in the art of onchocerciasis and parasitic infections treatment using plant recipes. A total of one hundred people were interviewed in villages found in the Far North region of Cameroon: 43 were females and 57 males, among which, 71 were recognized as traditional healers. Adults were the most represented (71 respondents). The study identified 96 plant species belonging to 49 genera divided into 29 families among which the most represented was the Fabaceae (20 quotes). The most represented biotope was savannah (98%) and trees (51) were the most used followed by shrub (41). The leaves (40) are the organs which are mostly demanded and the main preparation method is a decoction (69) and 36 diseases and / or symptoms related to onchocerciasis and helminthiases were recorded. The medicinal plants identified, constitute an undeniable asset and a good database for the biological screening of plant-based antiparasitic molecules, which can lead to the manufacture of improved traditional medicines.

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Ethnobotanical survey of medicinal plants used as anthelmintic remedies in Gabon

Cited by 25 publications

References 112 publications

Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

Countrywide Survey of Plants Used for Liver Disease Management by Traditional Healers in Burkina Faso

Essential oils of Citrus aurantifolia, Anthemis nobile and Lavandula officinalis: in vitro anthelmintic activities against Haemonchus contortus

Ethnobotanical study of plants used against onchocerciasis in the far north region of Cameroon

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