“…Prickly pears are oval shaped fruits commonly referred to as "tunas" (Figure 1) and are extensively distributed throughout Mexico [8]. They have been known to contain flavonoids, phenolic acids (caffeic, coumaric, vanillic, among others), betalains, ascorbic acid, fatty acids, lignans, and sterols [3,6]. Additionally, they possess a variety of health benefits, yet not restricted to a high antioxidant capacity [9], including cytotoxic activity [10,11], and an antiproliferative effect on cancer colon (HT29/Caco-2) and prostate cancer cell lines (PC-3) in vitro [12,13].…”